Meclizine/Buclizine/Cyclizine (Systemic)
Before Using This MedicineIf you are taking this medicine
without a prescription, carefully read and follow any precautions on the label.
For buclizine, cyclizine, and meclizine, the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to buclizine, cyclizine, or meclizine. Also tell your health
care professional if you are allergic to any other substances, such as foods,
preservatives, or dyes.
Pregnancy - These medicines have not been shown to cause birth
defects or other problems in humans. However, studies in animals have shown
that buclizine, cyclizine, and meclizine given in doses many times the usual
human dose cause birth defects, such as cleft palate.
Breast-feeding - Although these medicines may pass into breast
milk, they have not been reported to cause problems in nursing babies. However,
since these medicines tend to decrease the secretions of the body, it is possible
that the flow of breast milk may be reduced in some patients.
Children - There is no specific information comparing use
of buclizine, cyclizine, and meclizine in children with use in other age groups.
However, children may be especially sensitive to the anticholinergic effects
(e.g., dryness of mouth, nose, and throat) of these medicines.
Older adults - There is no specific information comparing use
of buclizine, cyclizine, and meclizine in the elderly with use in other age
groups. Many medicines have not been studied specifically in older people.
Therefore, it may not be known whether they work exactly the same way they
do in younger adults. However, older people may be especially sensitive to
the anticholinergic effects (e.g., constipation; difficult urination; dryness
of mouth, nose, and throat) of these medicines.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
buclizine, cyclizine, or meclizine, it is especially important that your health
care professional know if you are taking the following:
-
Central nervous system (CNS) depressants, other (medicines that make
you drowsy or less alert) or
-
Tricyclic antidepressants (medicine for depression) - Use with
buclizine, cyclizine, or meclizine may increase the side effects of either
medicine
Other medical problems - The presence of other medical problems may affect
the use of buclizine, cyclizine, or meclizine. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Asthma, bronchitis, emphysema, or other chronic lung disease - Cyclizine
or meclizine may cause serious breathing problems in patients who have any
of these conditions
-
Enlarged prostate or
-
Glaucoma or
-
Intestinal blockage or
-
Urinary tract blockage - Buclizine, cyclizine, or meclizine may
make these conditions worse
-
Heart failure - Cyclizine may make the condition worse
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