Brand Names : Hiprex, Mandelamine, Urex, Hip-Rex
Proper Use of This Medicine
start taking this medicine, check your urine with phenaphthazine paper or
another test to see if it is acid. Your urine must be
acidic (pH 5.5 or below) for this medicine to work properly
. If you
have any questions about this, check with your health care professional.
The following changes in your diet may help make your urine more acid;
however, check with your doctor first if you are on a special diet (for example,
for diabetes). Avoid most fruits (especially citrus fruits and juices), milk
and other dairy products, and other foods that make the urine less acid. Also,
avoid antacids unless otherwise directed by your doctor. Eating more protein
and foods such as cranberries (especially cranberry juice with vitamin C added),
plums, or prunes may also help. If your urine is still not acid enough, check
with your doctor.
If this medicine causes nausea or upset stomach, it may be taken after
meals and at bedtime.
For patients taking the dry granule form of this medicine
Dissolve the contents of each packet in 2 to 4 ounces of cold water
immediately before taking. Stir well. Be sure to drink all the liquid to get
the full dose of medicine.
For patients taking the oral liquid form of this medicine
Use a specially marked measuring spoon or other device to measure
each dose accurately. The average household teaspoon may not hold the right
amount of liquid.
For patients taking the enteric-coated tablet form
of this medicine
Swallow tablets whole. Do not break, crush, or take if chipped.
To help clear up your infection completely, keep taking
this medicine for the full time of treatment
, even if you begin to
feel better after a few days. Do not miss any doses
Dosing - The dose of methenamine will be different for
different patients. Follow your doctor's orders or the
directions on the label
. The following information includes only the
average doses of methenamine. If your dose is different,
do not change it
unless your doctor tells you to do so.
The number of tablets or teaspoonfuls of solution or suspension that you
take depends on the strength of the medicine.
For the treatment of urinary tract infections:
dosage form (methenamine hippurate
Adults and children 12 years of age and over - 1 gram two times
a day. Take in the morning and the evening.
Children up to 6 years of age - Use and dose must be determined
by your doctor.
Children 6 to 12 years of age - 500 milligrams (mg) to 1 gram
two times a day. Take in the morning and the evening.
dosage form (methenamine mandelate
enteric-coated tablets, regular tablets, solution, and suspension):
Adults and children 12 years of age and over - 1 gram four times
a day. Take after meals and at bedtime.
Children up to 6 years of age - Dose is based on body weight.
The usual dose is 18.3 mg per kilogram (kg) (8.3 mg per pound) of body weight
four times a day. Take after meals and at bedtime.
Children 6 to 12 years of age - 500 mg four times a day. Take
after meals and at bedtime.
Missed dose - If you miss a dose of this medicine, take it as
soon as possible. However, if it is almost time for your next dose, skip the
missed dose and go back to your regular dosing schedule. Do not double doses.
Storage - To store this medicine:
Keep out of the reach of children.
Store away from heat and direct light.
Do not store the dry granule or tablet form of this medicine in the
bathroom, near the kitchen sink, or in other damp places. Heat or moisture
may cause the medicine to break down.
Keep the oral liquid form of this medicine from freezing.
Do not keep outdated medicine or medicine no longer needed. Be sure
that any discarded medicine is out of the reach of children.