Methotrexate For Noncancerous Conditions (Systemic)
Brand Names : Folex, Folex PFS, Methotrexate LPF, Rheumatrex, amethopterin
Precautions While Using This Medicine
It is very important that your doctor check your progress at
to make sure that this medicine is working properly
and to check for unwanted effects.
Do not drink alcohol while using this medicine
Alcohol can increase the chance of liver problems.
Some patients who take methotrexate may become more sensitive to sunlight
than they are normally. When you first begin taking methotrexate, avoid too
much sun and do not use a sunlamp until you see how you react to the sun,
especially if you tend to burn easily. In case of a severe burn, check with
your doctor. This is especially important if you are taking this medicine
for psoriasis because sunlight can make the psoriasis worse.
Do not take medicine for inflammation or pain (aspirin
or other salicylates, diclofenac, diflunisal, fenoprofen, ibuprofen, indomethacin,
ketoprofen, meclofenamate, mefenamic acid, naproxen, phenylbutazone, piroxicam,
sulindac, suprofen, tolmetin) without first checking with your doctor
These medicines may increase the effects of methotrexate, which could be harmful.
While you are being treated with methotrexate, and after you stop treatment
with it, do not have any immunizations (vaccinations)
without your doctor's approval
. Methotrexate may lower your body's
resistance and there is a chance you might get the infection the immunization
is meant to prevent. In addition, other persons living in your household should
not take or should not have recently taken oral polio vaccine since there
is a chance they could pass the polio virus on to you. Also, avoid other persons
who have taken oral polio vaccine. Do not get close to them, and do not stay
in the same room with them for very long. If you cannot take these precautions,
you should consider wearing a protective face mask that covers the nose and
Methotrexate can lower the number of white blood cells in your blood temporarily,
increasing the chance of getting an infection. It can also lower the number
of platelets, which are necessary for proper blood clotting. If this occurs,
there are certain precautions you can take, especially when your blood count
is low, to reduce the risk of infection or bleeding:
If you can, avoid people with infections. Check
with your doctor immediately
if you think you are getting an infection
or if you get a fever or chills, cough or hoarseness, lower back or side pain,
or painful or difficult urination.
Check with your doctor immediately
you notice any unusual bleeding or bruising; black, tarry stools; blood in
urine or stools; or pinpoint red spots on your skin.
Be careful when using a regular toothbrush, dental floss, or toothpick.
Your medical doctor, dentist, or nurse may recommend other ways to clean your
teeth and gums. Check with your medical doctor before having any dental work
Do not touch your eyes or the inside of your nose unless you have
just washed your hands and have not touched anything else in the meantime.
Be careful not to cut yourself when you are using sharp objects such
as a safety razor or fingernail or toenail cutters.
Avoid contact sports or other situations where bruising or injury