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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Methyldopa and Thiazide Diuretics

Methyldopa and Thiazide Diuretics (Systemic)

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects

  • Antihypertensive

Combinations of methyldopa and a thiazide diuretic (chlorothiazide or hydrochlorothiazide) are used to treat high blood pressure (hypertension).

High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Methyldopa works by controlling nerve impulses along certain nerve pathways. As a result, it relaxes blood vessels so that blood passes through them more easily. Thiazide diuretics help reduce the amount of water in the body by increasing the flow of urine. These actions help to lower blood pressure.

This medicine is available only with your doctor's prescription, in the following dosage forms:

  • Methyldopa and Chlorothiazide
    • Tablets (U.S. and Canada)
  • Methyldopa and Hydrochlorothiazide
    • Tablets (U.S. and Canada)

Brand Names

Some commonly used brand names are:

In the U.S. -

  • Aldoclor 1
  • Aldoril 2

In Canada -

  • Novodoparil 2
  • PMS Dopazide 2
  • Supres 1


For quick reference, the following medicines are numbered to match the corresponding brand names.

This information applies to the following medicines:
1. Methyldopa and Chlorothiazide (meth-il-DOE-pa and klor-oh-THYE-a-zide)‡
2. Methyldopa and Hydrochlorothiazide (meth-il-DOE-pa and hye-droe-klor-oh-THYE-a-zide)‡
‡ Generic name product may be available in the U.S.


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Methyldopa and Thiazide Diuretics: Before Using

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