Misoprostol (Systemic)
Brand Names : Cytotec
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For misoprostol, the
following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to misoprostol. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Misoprostol must not be used
during pregnancy
when used to prevent stomach ulcers caused by anti-inflammatory
medicines including aspirin. It has been shown to cause contractions and bleeding
of the uterus. Misoprostol may also cause miscarriage. Before starting to take this medicine you must have had a negative pregnancy
test within the previous 2 weeks. Also, you must start taking misoprostol
only on the second or third day of your next normal menstrual period. In addition,
it will be necessary that you use an effective form of birth control while
taking this medicine. Be sure that you have discussed this with your doctor
before taking this medicine.
Breast-feeding - It is not known whether misoprostol passes into
breast milk. However, misoprostol is not recommended for use during breast-feeding
because it may cause diarrhea in nursing babies.
Children - Studies on this medicine have been done only in adult
patients, and there is no specific information comparing use of misoprostol
in children with use in other age groups.
Older adults - This medicine has been tested and has not been shown
to cause different side effects or problems in older people than it does in
younger adults.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. Tell your health care
professional if you are taking any other prescription or nonprescription (over-the-counter
[OTC]) medicine.
Other medical problems - The presence of other medical
problems may affect the use of misoprostol. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Blood vessel disease - Medicines similar to misoprostol have
been shown to make this condition worse
-
Epilepsy (uncontrolled) - Medicines similar to misoprostol have
been shown to cause convulsions (seizures)
-
Inflammatory bowel disease - Misoprostol may worsen diarrhea,
which could lead to dehydration
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