Muromonab-CD3 (Systemic)
Brand Names : Orthoclone OKT3
Precautions While Using This MedicineIt is very important that your doctor check your progress at regular visits
to make sure that this medicine is working properly and to check for
unwanted effects.
While you are being treated with muromonab-CD3 and after you stop treatment
with it, do not have any immunizations (vaccinations)
without your doctor's approval
. Muromonab-CD3 may lower your body's
resistance. For some immunizations, there is a chance you might get the infection
the immunization is meant to prevent. For other immunizations, it may be especially
important to receive the immunization to prevent a disease. In addition, other
persons living in your house should not take oral polio vaccine since there
is a chance they could pass the polio virus on to you. Also, avoid persons
who have recently taken oral polio vaccine. Do not get close to them and do
not stay in the same room with them for very long. If you cannot take these
precautions, you should consider wearing a protective face mask that covers
the nose and mouth.
Treatment with muromonab-CD3 may also increase the chance of getting other
infections. If you can, avoid people with colds or other infections. If you
think you are getting a cold or other infection, check with your doctor.
This medicine commonly causes chest pain, dizziness, fever and chills,
shortness of breath, stomach upset, and trembling within a few hours after
the first dose. These effects should be less after the second dose. However,
check with your doctor or nurse immediately
if
you have chest pain, rapid or irregular heartbeat, shortness of breath or
wheezing, or swelling of the face or throat after any dose.
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