Narcotic Analgesics and Aspirin (Systemic)
Precautions While Using This Medicine
will be taking this medicine for a long time (for example, for several months
at a time), your doctor should check your progress at regular visits.
Check the labels of all nonprescription (over-the-counter
[OTC]) and prescription medicines you now take. If any contain a narcotic,
aspirin, or other salicylates, check with your health care professional
Taking them together with this medicine may cause an overdose.
This medicine will add to the effects of alcohol and other CNS depressants
(medicines that slow down the nervous system, possibly causing drowsiness).
Some examples of CNS depressants are antihistamines or medicine for hay fever,
other allergies, or colds; sedatives, tranquilizers, or sleeping medicine;
other prescription pain medicine or narcotics; barbiturates; medicine for
seizures; muscle relaxants; or anesthetics, including some dental anesthetics.
Also, stomach problems may be more likely to occur if you drink alcoholic
beverages while you are taking aspirin. Do not drink
alcoholic beverages, and check with your medical doctor or dentist before
taking any of the medicines listed above, while you are using this medicine
Taking acetaminophen or certain other medicines together with the aspirin
in this combination medicine may increase the chance of unwanted effects.
The risk will depend on how much of each medicine you take every day, and
on how long you take the medicines together. If your medical doctor or dentist
directs you to take these medicines together on a regular basis, follow his
or her directions carefully. However, do not take acetaminophen or any of
the following medicines together with this combination medicine for more than
a few days, unless your medical doctor or dentist has directed you to do so
and is following your progress:
Diclofenac (e.g., Voltaren)
Diflunisal (e.g., Dolobid)
Etodolac (e.g., Lodine)
Fenoprofen (e.g., Nalfon)
Floctafenine (e.g., Idarac)
Flurbiprofen, oral (e.g., Ansaid)
Ibuprofen (e.g., Motrin)
Indomethacin (e.g., Indocin)
Ketoprofen (e.g., Orudis)
Ketorolac (e.g., Toradol)
Meclofenamate (e.g., Meclomen)
Mefenamic acid (e.g., Ponstel)
Nabumetone (e.g., Relafen)
Naproxen (e.g., Naprosyn)
Oxaprozin (e.g., Daypro)
Phenylbutazone (e.g., Butazolidin)
Piroxicam (e.g., Feldene)
Sulindac (e.g., Clinoril)
Tenoxicam (e.g., Mobiflex)
Tiaprofenic acid (e.g., Surgam)
Tolmetin (e.g., Tolectin)
This medicine may cause some people to become drowsy, dizzy, or lightheaded,
or to feel a false sense of well-being. Make sure you
know how you react to this medicine before you drive, use machines, or do
anything else that could be dangerous if you are dizzy or are not alert and
Dizziness, lightheadedness, or fainting may occur, especially when you
get up suddenly from a lying or sitting position. Getting up slowly may help
lessen this problem.
Nausea or vomiting may occur, especially after the first couple of doses.
This effect may go away if you lie down for a while. However, if nausea or
vomiting continues, check with your doctor. Lying down for a while may also
help some other side effects, such as dizziness or lightheadedness.
Before having any kind of surgery (including dental surgery) or emergency
treatment, tell the medical doctor or dentist in charge that you are taking
Do not take this medicine for 5 days before any surgery, including dental
surgery, unless otherwise directed by your medical doctor or dentist. Taking
aspirin during this time may cause bleeding problems.
For patients taking the buffered aspirin, codeine,
combination (C2 Buffered with Codeine):
This product contains antacids that can keep many other medicines,
especially some medicines used to treat infections, from working properly.
This problem can be prevented by not taking the 2 medicines too close together.
Ask your pharmacist how long you should wait between taking any other medicine
and the buffered aspirin, codeine, and caffeine combination.
For diabetic patients
False urine sugar test results may occur if you are regularly taking
8 or more 325-mg (5-grain) or 5 or more 500-mg doses of aspirin a day. Smaller
amounts or occasional use of aspirin usually will not affect urine sugar tests.
If you have any questions about this, check with your health care professional,
especially if your diabetes is not well controlled.
Narcotic analgesics may cause dryness of the mouth. For temporary relief,
use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva
substitute. However, if dry mouth continues for more than 2 weeks, check with
your dentist. Continuing dryness of the mouth may increase the chance of dental
disease, including tooth decay, gum disease, and fungus infections.
If you have been taking this medicine regularly for several weeks or more,
do not suddenly stop using it without first checking
with your doctor
. Depending on which of these medicines you have been
taking, and the amount you have been taking every day, your doctor may want
you to reduce gradually the amount you are taking before stopping completely,
to lessen the chance of withdrawal side effects.
If you think you or someone else may have taken an
overdose of this medicine, get emergency help at once
. Taking an overdose
of this medicine or taking alcohol or CNS depressants with this medicine may
lead to unconsciousness or death. Signs of overdose of this medicine include
convulsions (seizures); hearing loss; confusion; ringing or buzzing in the
ears; severe excitement, nervousness, or restlessness; severe dizziness, severe
drowsiness, shortness of breath or troubled breathing, and severe weakness.