Nifurtimox (Systemic)
Brand Names : Lampit, Bayer 2502
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For nifurtimox, the
following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to nifurtimox. Also tell your health care professional if
you are allergic to any other substances, such as foods, preservatives, or
dyes.
Pregnancy - Studies have not been done in pregnant women. In
animal studies, this medicine has not been shown to cause birth defects. However,
when used in very large doses, nifurtimox caused a decrease in the weight
of the offspring.
Breast-feeding - It is not known whether nifurtimox passes into
human breast milk. Although most medicines pass into breast milk in small
amounts, many of them may be used safely while breast-feeding. Mothers who
are taking this medicine and who wish to breast-feed should discuss this with
their doctor.
Children - Although there is no specific information comparing
use of nifurtimox in children with use in other age groups, this medicine
is not expected to cause different side effects or problems in children than
it does in adults.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults or if they cause different side effects
or problems in older people. There is no specific information comparing use
of nifurtimox in the elderly with use in other age groups.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
nifurtimox, it is especially important that your health care professional
know if you are taking any of the following:
-
Alcohol - Taking alcohol with nifurtimox may cause unwanted effects
Other medical problems - The presence of other medical
problems may affect the use of nifurtimox. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Alcohol and/or drug abuse (or history of) or
-
Allergies, especially of skin (or history of) or
-
Convulsions (seizures) and other brain disease (or history of) or
-
Nerve disease, such as numbness, tingling, pain, or weakness in hands
or feet (or history of) - Nifurtimox may make these conditions worse
-
Kidney disease or
-
Liver disease - Higher blood levels of nifurtimox may result,
which may increase the chance of side effects
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