Peginterferon alfa-2b (Systemic)
Brand Names : PEG-Intron
Before Using This MedicineIn deciding to use a medicine, the risks of taking the medicine must be
weighed against the good it will do. This is a decision you and your doctor
will make. For peginterferon alfa-2b, the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual
or allergic reaction to peginterferon alfa-2b. Also tell your health care
professional if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Peginterferon alfa-2b has not been studied in pregnant
women. However, studies in animals have shown that peginterferon alfa-2b causes
death of the fetus. Before taking this medicine, make sure your doctor knows
if you are pregnant or if you may become pregnant.
Breast-feeding - It is not known whether peginterferon alfa-2b
passes into the breast milk. However, peginterferon alfa-2b is not recommended
during breast-feeding because it may cause unwanted effects in nursing babies.
Children - Studies on this medicine have been done only in
adult patients, and there is no specific information comparing use of peginterferon
alfa-2b in children with use in other age groups.
Older adults - This medicine has been tested in a limited number
of patients 65 years of age or older and has not been shown to cause different
side effects or problems in older people than it does in younger adults.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. Tell your health care
professional if you are taking any other prescription or nonprescription (over-the-counter
[OTC]) medicine.
Other medical problems - The presence of other medical problems may affect the use of peginterferon
alfa-2b. Make sure you tell your doctor if you have any other medical problems,
especially:
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Autoimmune hepatitis - May cause severe disease affecting other
parts of the body
-
Decompensated liver disease - May cause liver disease to become
worse
-
Diabetes mellitus (sugar diabetes) or
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Heart or blood vessel disease or
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Hyperglycemia (high blood sugar) or
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Kidney disease or
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Lung disease
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Psoriasis or
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Psychiatric problems or
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Rheumatoid arthritis or
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Systemic lupus erythematosus or
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Thyroid disease - May be worsened by peginterferon alfa-2b
-
Human immunodeficiency virus (HIV) infection or
-
Liver or other organ transplant - It is not known if peginterferon
alfa-2b will work in patients with these conditions
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