Perphenazine and Amitriptyline (Systemic)
Brand Names : Etrafon, Etrafon-A, Etrafon-Forte, Triavil, Elavil Plus, Etrafon-D, Etrafon-F, PMS Levazine
Side Effects of This MedicineAlong with its needed effects, perphenazine (included in this combination
medicine) can sometimes cause serious side effects. Tardive dyskinesia (a
movement disorder) may occur and may not go away after you stop using the
medicine. Signs of tardive dyskinesia include fine, worm-like movements of
the tongue, or other uncontrolled movements of the mouth, tongue, cheeks,
jaw, or arms and legs. Other serious but rare side effects may also occur.
These include severe muscle stiffness, fever, unusual tiredness or weakness,
fast heartbeat, difficult breathing, increased sweating, loss of bladder control,
and seizures (neuroleptic malignant syndrome). You and
your doctor should discuss the good this medicine will do as well as the risks
of taking it
.
Stop taking this medicine
and get emergency help immediately
if any of the following side effects
occur:
Also, check
with your doctor as soon as possible if any of the following side effects
occur:
More common
Blurred vision or any change in vision; difficulty in speaking or swallowing; fainting; inability to move eyes; lip smacking
or puckering; loss of balance control; mask-like face; muscle spasms, especially
of face, neck, and back; nervousness, restlessness,
or need to keep moving; puffing of cheeks; rapid or fine, worm-like movements of tongue; shuffling walk; stiffness of arms and legs; trembling and shaking of fingers and hands; tic-like or twitching movements; twisting movements
of body; uncontrolled chewing movements; uncontrolled movements of arms or legs; weakness of arms and legs
Less common
Confusion; constipation; difficult urination; eye pain; hallucinations (seeing, hearing, or feeling things that are not
there); increased skin sensitivity to sun; shakiness; slow pulse or irregular heartbeat
Rare
Abdominal or stomach pain; aching muscles
or joints; back or leg pain; fever and chills; hair loss; hot, dry skin or lack of sweating; irritability; loss of appetite; muscle weakness or
twitching; nausea, vomiting, or diarrhea; nosebleeds; prolonged, painful, inappropriate
penile erection; ringing, buzzing, or other unexplained
noises in ears; skin discoloration; skin rash and itching; sore throat and
fever; swelling of face and tongue; swelling of testicles; unusual bleeding
or bruising; yellow eyes or skin
Symptoms of overdose
Agitation; confusion; convulsions (seizures); drowsiness (severe); enlarged pupils; fast, slow, or irregular
heartbeat; fever; hallucinations
(seeing, hearing, or feeling things that are not there); shortness of breath or troubled breathing; unusual
tiredness or weakness (severe); vomiting (severe)
Other side effects may occur that usually do not need medical
attention. These side effects may go away during treatment as your body adjusts
to the medicine. However, check with your doctor if any of the following side
effects continue or are bothersome:
After you stop using this medicine, your body
may need time to adjust. The length of time this takes depends on the amount
of medicine you are using and how long you used it. During this time, check
with your doctor if you notice any of the following symptoms:
Dizziness; nausea or vomiting; stomach pain; trembling of fingers and
hands; symptoms of tardive dyskinesia, including
lip smacking or puckering, puffing of cheeks, rapid or fine, worm-like movements
of tongue, uncontrolled chewing movements, or uncontrolled movements of arms
or legs Other
side effects may occur if the medicine is stopped suddenly or stopped after
long-term treatment. Check with your doctor if you notice any of the following
symptoms:
Diarrhea; headache; irritability; restlessness; trouble in sleeping, with vivid dreams; unusual excitement Other side effects not listed above may
also occur in some patients. If you notice any other effects, check with your
doctor.
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