Poliovirus Vaccine (Systemic)

Side Effects of This Vaccine

In very rare instances (approximately 1 case in 760,000 doses), healthy persons who have taken the oral vaccine (OPV) and healthy persons who are close contacts of adults or children who have taken OPV have been infected by the polio virus and have become paralyzed. No paralysis caused by polio infection has occurred with the injected vaccine (IPV) since 1955.

Along with its needed effects, a vaccine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Get emergency help immediately if any of the following side effects occur:

Symptoms of allergic reaction

Difficulty in breathing or swallowing; hives; itching, especially of feet or hands; reddening of skin, especially around ears; swelling of eyes, face, or inside of nose; unusual tiredness or weakness (sudden and severe)

More common

Other side effects may occur that usually do not need medical attention. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Irritability; loss of appetite; tiredness

Less common - with injection

Itching or skin rash; redness, soreness, hard lump, tenderness, or pain at the place of injection

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.