Pralidoxime (Systemic)
Brand Names : Protopam Chloride, 2-PAM, 2-PAM chloride
Category- Antidote, to cholinesterase inhibitors
- Antidote, to organophosphate chemicals
- Antidote, to organophosphate pesticides
DescriptionPralidoxime (pra-li-DOX-eem) is used together with another medicine called
atropine to treat poisoning caused by organic phosphorus pesticides (e.g.,
diazinon, malathion, mevinphos, parathion, and sarin) and by organophosphate
chemicals (�nerve gases�) used in chemical warfare. Pralidoxime
is also used to treat overdose of medicines, such as ambenonium, neostigmine,
and pyridostigmine, that are used to treat myasthenia gravis. Poisoning with
these chemicals or medicines causes your muscles, including the muscles that
help you breathe, to become weak. Pralidoxime is used to help you get back
strength in your muscles.
Pralidoxime is to be given only by or under the direct supervision of a
doctor or trained military personnel. It is available in the following dosage
form:
Parenteral
-
Injection (U.S. and Canada)
Brand NamesSome commonly used brand names are:
In the U.S. -
In Canada -
Generic name product may be available in the U.S.
Other commonly used names are 2-PAM
and 2-PAM chloride
.
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