Quinacrine (Systemic)
Brand Names : Mepacrine
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For Quinacrine], the
following should be considered:
Allergies - Tell your doctor if you have ever had any unusual
or allergic reaction to quinacrine. Also tell your doctor and pharmacist if
you are allergic to any other substances, such as foods, preservatives, or
dyes.
Pregnancy - Quinacrine crosses the placenta, and its use in
pregnant women is generally not recommended.
Breast-feeding - Quinacrine passes into breast milk. However,
quinacrine has not been reported to cause problems in nursing babies.
Children - Children tolerate the oral dosage form of quinacrine
less well than do adults, and it may cause vomiting in children due to its
bitter taste.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults. Although there is no specific information
comparing use of quinacrine in the elderly with use in other age groups, this
medicine is not expected to cause different side effects or problems in older
people than it does in younger adults.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
quinacrine, it is especially important that your doctor and pharmacist know
if you are taking any of the following:
-
Alcohol or alcohol-containing medicines - Use with quinacrine
may increase the chance of side effects of alcohol.
-
Primaquine - Use with quinacrine may increase the chance of serious
side effects of primaquine; primaquine shouldnot
be
taken when you are taking quinacrine.
Other medical problems - The presence of other medical
problems may affect the use of quinacrine. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Alcoholism (or history of) or
-
Liver disease - Quinacrine may cause additional liver problems
-
Mental illness (severe) (history of) - Quinacrine may cause mood
or other mental changes in some patients.
-
Porphyria - Quinacrine may make porphyria worse.
-
Psoriasis - Quinacrine may cause an attack of psoriasis or make
psoriasis worse; patients with psoriasis should not
take quinacrine.
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