Radiopaque Agents Diagnostic (Local)

Before Having This Test

In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, test results may be affected by other things. For radiopaque agents the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to iodine, to products containing iodine (for example, iodine-containing foods, such as seafoods, cabbage, kale, rape [turnip-like vegetable], turnips, or iodized salt), or to other radiopaque agents. Also tell your doctor if you are allergic to any other substances, such as sulfites or other preservatives.

Pregnancy - Studies on effects in pregnancy when radiopaque agents are instilled into the bladder or ureters have not been done in women. Studies in animals have been done only with iothalamate, which has not been shown to cause birth defects or other problems.

Diagnostic tests of the uterus and fallopian tubes using radiopaque agents are not recommended during pregnancy or for at least 6 months after a pregnancy has ended. The test may cause other problems, such as infection in the uterus.

Also, radiopaque agents containing iodine have, on rare occasions, caused hypothyroidism (underactive thyroid) in the baby when they were injected into the amniotic sac late in the pregnancy. In addition, x-rays of the abdomen during pregnancy may have harmful effects on the fetus. Make sure your doctor knows if you are pregnant or if you suspect that you may be pregnant when you are to receive this radiopaque agent.

Breast-feeding - Although small amounts of radiopaque agents are absorbed into the body and may pass into the breast milk, these agents have not been shown to cause problems in nursing babies. However, it may be necessary for you to stop breast-feeding temporarily after receiving a radiopaque agent. Be sure you have discussed this with your doctor.

Children - Although there is no specific information comparing use of radiopaque agents in children with use in other age groups, these agents are not expected to cause different side effects or problems in children than they do in adults when used in the bladder or ureters. There is no specific information about the use of radiopaque agents in children for studies of the uterus or fallopian tubes.

Older adults - Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of radiopaque agents for instillation into the bladder or ureters or into the uterus and fallopian tubes in the elderly with use in other age groups, these agents are not expected to cause different side effects or problems in older people than they do in younger adults.

Other medical problems - The presence of other medical problems may affect the use of radiopaque agents. Make sure you tell your doctor if you have any other medical problems, especially:

• Asthma, hay fever, or other allergies (history of) or
• Reaction to a skin test for allergies or to penicillins - If you have a history of these conditions, there is a greater chance of having a reaction, such as an allergic reaction, to the radiopaque agent

• Enlarged prostate or
• Kidney disease (severe) - There may be blockage that makes it difficult or impossible to put the solution of the radiopaque agent into the bladder or ureters

• Genital tract infection or
• Urinary tract infection - The risk of complications is greater in patients with these conditions

• Pelvic inflammatory disease (severe) - The condition may be aggravated by this test

Preparation for This Test

Your doctor may have special instructions for you in preparation for your test, such as the need for a special diet or for a laxative, enema, or vaginal douche, depending on the kind of test you are having done. If you have not received such instructions or if you do not understand them, check with your doctor in advance.

For your comfort and for best test results, you may be instructed to urinate just before the procedure.