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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Rauwolfia Alkaloids and Thiazide Diuretics

Rauwolfia Alkaloids and Thiazide Diuretics (Systemic)

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects

  • Antihypertensive - Deserpidine and Hydrochlorothiazide; Deserpidine and Methyclothiazide; Rauwolfia Serpentina and Bendroflumethiazide; Reserpine and Chlorothiazide; Reserpine and Chlorthalidone; Reserpine and Hydrochlorothiazide; Reserpine and Methyclothiazide

Rauwolfia alkaloid and thiazide diuretic combinations are used in the treatment of high blood pressure (hypertension).

High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Rauwolfia alkaloids work by controlling nerve impulses along certain nerve pathways. As a result, they act on the heart and blood vessels to lower blood pressure. Thiazide diuretics help to reduce the amount of water in the body by increasing the flow of urine. This also helps to lower blood pressure.

These medicines are available only with your doctor's prescription, in the following dosage forms:

  • Deserpidine and Hydrochlorothiazide
    • Tablets (U.S.)
  • Deserpidine and Methyclothiazide
    • Tablets (U.S. and Canada)
  • Rauwolfia Serpentina and Bendroflumethiazide
    • Tablets (U.S.)
  • Reserpine and Chlorothiazide
    • Tablets (U.S.)
  • Reserpine and Chlorthalidone
    • Tablets (U.S.)
  • Reserpine and Hydrochlorothiazide
    • Tablets (Canada)
  • Reserpine and Methyclothiazide
    • Tablets (U.S.)

Brand Names

Some commonly used brand names are:

In the U.S. -

  • Demi-Regroton 5
  • Diupres 4
  • Diurigen with Reserpine 4
  • Diutensen-R 7
  • Enduronyl 2
  • Enduronyl Forte 2
  • Oreticyl 1
  • Oreticyl Forte 1
  • Rauzide 3
  • Regroton 5

In Canada -

  • Dureticyl 2
  • Hydropres-50 6


For quick reference, the following rauwolfia alkaloids and thiazide diuretics are numbered to match the corresponding brand names.

This information applies to the following medicines:
1. Deserpidine and Hydrochlorothiazide (de-SER-pi-deen and hye-droe-klor-oh-THYE-a-zide)†
2. Deserpidine and Methyclothiazide (de-SER-pi-deen and meth-i-kloe-THYE-a-zide)‡
3. Rauwolfia Serpentina and Bendroflumethiazide (rah-WOOL-fee-a ser-pen-TEE-na and ben-droe-floo-meth-EYE-a-zide)†
4. Reserpine and Chlorothiazide (re-SER-peen and klor-oh-THYE-a-zide)†‡
5. Reserpine and Chlorthalidone (re-SER-peen and klor-THAL-i-done)†
6. Reserpine and Hydrochlorothiazide (re-SER-peen and hye-droe-klor-oh-THYE-a-zide)*‡
7. Reserpine and Methyclothiazide (re-SER-peen and meth-i-kloe-THYE-a-zide)†
* Not commercially available in the U.S.
† Not commercially available in Canada
‡ Generic name product may be available in the U.S.


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Rauwolfia Alkaloids and Thiazide Diuretics: Before Using

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