Sodium Oxybate (Systemic)
Brand Names : Xyrem, GHB
Proper Use of This Medicine
Dosing - The dose of sodium oxybate will
be different for different patients. Follow your healthcare
professional's orders or the directions in the medication guide that comes
with your medicine. It is very important that you carefully read and follow
all instructions before using sodium oxybate.
Your healthcare professional
must instruct you in the safe and effective use of sodium oxybate. If you
have any questions about sodium oxybate, ask your healthcare professional
or call the central pharmacy that sent you the medicine at the toll free number
1-866-997-3688. The following information includes only
the average doses of sodium oxybate. If your dose is
different, do not change it
unless your healthcare professional tells
you to do so.
dosage form (oral solution):
For treatment of cataplexy
Adults - 2.25 grams given at bedtime and repeated one time during
the night. The first dose should be taken at bedtime and the second dose taken
2.5 to 4 hours later. The dose will be increased as needed by your healthcare
professional up to a maximum of 9 grams.
Food will decrease the amount of sodium oxybate that is absorbed by your
body. It it best to take this medicine several hours after a meal.
To take sodium oxybate, you must first mix it with water. Your healthcare
professional and the medication guide that comes with your medicine will tell
you how to prepare sodium oxybate. Prepare both doses before
bedtime. Place the caps provided on the dosing cups and turn each
cap so it locks in its child resistant position.
Sodium oxybate causes sleep very quickly. Take it only at bedtime
and while in bed. Drink all of the first dose while sitting in bed, recap
the cup, and then lie down right away. Right before going to sleep place your
second dose (already prepared) in a secure location (locked if needed) near
your bed. You may need to set an alarm to wake up to take the second dose.
When you wake up to take the second dose, remove the cap from the second dosing
cup. While sitting in bed, drink all of the second dose right before lying
down to continue sleeping. Recap the second cup.
Missed dose - If you miss a dose of this medicine, take it
as soon as possible. If you miss the second dose, skip that dose and do not
take sodium oxybate again until the next day. Never take two doses of sodium
oxybate at the same time. If you have any questions about this ask your healthcare
Storage - To store this medicine:
Store in the original bottle in a safe and secure place (locked up
Keep out of the reach of children and pets.Always
place your nightly doses of sodium oxybate out of the reach of children.
Do not keep any outdated medicine or medicine that is no longer needed.
Pour any unused sodium oxybate down the drain
Destroy the drug name on the label with a marker when you are finished
with the medicine.
Place the empty bottle in the trash so it is not used for illegal