Sodium Phenylbutyrate (Systemic)
Brand Names : Buphenyl
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For sodium phenylbutyrate,
the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to sodium phenylbutyrate. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Studies on effects in pregnancy have not been done
in either humans or animals.
Breast-feeding - It is not known whether sodium phenylbutyrate passes
into breast milk.
Children - This medicine has been reported to cause unwanted
side effects in children. Also, nerve problems and brain damage associated
with your condition may continue to worsen despite treatment.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults or if they cause different side effects
or problems in older people. There is no specific information comparing the
use of sodium phenylbutyrate in the elderly with use in other age groups.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
sodium phenylbutyrate, it is especially important that your health care professional
know if you are taking the following:
-
Probenecid - Probenecid may increase the effects of sodium phenylbutyrate
Other medical problems - The presence of other medical
problems may affect the use of sodium phenylbutyrate. Make sure you tell your
doctor if you have any other medical problems, especially:
-
Edema (swelling) or
-
Heart disease or
-
Kidney disease, severe - Increased retention of water may make
these conditions worse
-
Kidney disease or
-
Liver disease - Higher blood levels of sodium phenylbutyrate
may result and increase the risk of side effects
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