Sodium Thiosulfate : Proper Use (Cyanide Antidote Package)

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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Sodium Thiosulfate : Proper Use

Sodium Thiosulfate (Systemic)

Brand Names : Cyanide Antidote Package

Sodium Thiosulfate | Before Using | Proper Use | Side Effects

Proper Use of This Medicine

Dosing - The dose of sodium thiosulfate will be different for different patients. The following information includes only the average doses of sodium thiosulfate.

For injection dosage form:
- For use with cisplatin (a cancer medicine):
  - Adults and teenagers - The first dose, given just before the cancer medicine, is usually 4 grams per square meter of body surface area, injected into a vein. The second dose is started at the same time as the cancer medicine. It is usually 12 grams per square meter of body surface area, injected into a vein over a period of six hours.
- For cyanide poisoning:
  - Adults and teenagers - The usual dose is 12.5 grams injected into a vein at a rate of 0.625 to 1.25 grams (2.5 to 5 milliliters [mL]) per minute.
  - Children - The usual dose is 412.5 milligrams (mg) per kilogram (kg) (187 mg per pound) of body weight or 7 grams per square meter of body surface area injected into a vein at a rate of 0.625 to 1.25 grams (2.5 to 5 mL) per minute.

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