Treprostinil (Systemic)

Brand Names : Remodulin

Proper Use of This Medicine

Your doctor or nurse will teach you how to prepare the medicine and use the pump for administering the medicine. Treprostinil must be administered continuously by a portable pump that is operated by a small computer. The medicine will be delivered directly under your skin through a catheter.

The instructions for the use of the pump may vary depending on the particular make and model of the pump. Your doctor or nurse will give you detailed instructions on how to use and care for the particular pump and accessories that you will use for administering your medicine.

Dosing - The dose of treprostinil will be different for different patients and will be determined by your doctor. The amount of medicine you take may have to be increased gradually by your doctor. It must never be stopped suddenly. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of treprostinil. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the concentration of the medicine and the rate at which the infusion pump delivers the medicine.

• For injection dosage form:
  • For pulmonary arterial hypertension:
    • Adults - Initially, 1.25 nanograms per kilogram (kg) (0.6 nanogram per pound) of body weight per minute. Your doctor may increase or decrease your dose as necessary.
    • Children - Use and dose must be determined by your doctor.

Missed dose - Treprostinil has to be administered by a continuous intravenous infusion and it must never be stopped suddenly.

Storage - To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• If the medicine has particles in it or is discolored, it should be discarded.
• Do not keep outdated medicine, or medicine no longer needed. Ask your health care professional how you should dispose of any medicine you do not use. Be sure that any discarded medicine is out of the reach of children.