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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Altretamine (Oral)

Altretamine (By Mouth)


Treats ovarian cancer that has relapsed after chemotherapy.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to altretamine.

How to Use This Medicine:


  • This medicine, like all drugs used to treat cancer, is very strong. Make sure you understand why you are receiving it, and its risks and benefits.
  • This medicine must be taken on a schedule. Your doctor will prescribe your exact dose and tell you how often to take it. It is best to take this medicine after meals and at bedtime.
  • Do not take more of this medicine than your doctor ordered.
  • During your treatment, you may also receive other medicines to help prevent nausea and vomiting.

If a dose is missed:

  • Take your medicine as soon as possible.
  • If it is almost time for your next regular dose, take two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store this medicine at room temperature in a closed container, away from heat, moisture, and direct light.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also taking cimetidine (Tagamet®), vitamin B6 (pyridoxine), or medicine to treat depression.
Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • Taking this medicine during pregnancy can cause harm to the unborn baby. You should avoid becoming pregnant during your treatment.
  • Your doctor may want to check your blood at regular intervals while you are taking this medicine. Be sure to keep all appointments.
  • You may get infections more easily while you are taking altretamine. Stay away from crowds or people with colds, the flu, or other infections.
  • Chemotherapy causes nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it. Ask your doctor or nurse about other ways to control these side effects.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Numbness or tingling in arms, hands, legs, or feet
  • Unexplained fever, chills, or sore throat
  • Unusual bleeding or bruising
  • Unusual tiredness
  • Wheezing or trouble breathing

If you notice these less serious side effects, talk with your doctor:

  • Loss of appetite
  • Nausea and vomiting
If you notice other side effects that you think are caused by this medicine, tell your doctor.

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