Dinoprostone (Vaginal)
Dinoprostone (dye-noe-PROST-one)
Helps dilate the opening of the uterus (cervix) in a pregnant woman. Belongs to a class of drugs called prostaglandins.
Brand Name(s):Cervidil, Prostin E2, Prepidil
There may be other brand names for this medicine. When This Medicine Should Not Be Used:
You should not receive this medicine if you have had an allergic reaction to dinoprostone. How to Use This Medicine:
Insert, Suppository, Gel/Jelly
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You will receive this medicine in a hospital or clinic, unless otherwise directed by your doctor.
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A nurse or doctor will insert this medicine into your vagina so that the medicine comes into contact with your cervix. The nurse or doctor will need to use a speculum to insert the gel.
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The gel or suppository should be brought to room temperature just before being placed in the vagina.
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You will need to lie on your back for up to 2 hours after the insert is put in place. You will need to lie on your back for up to 30 minutes after the gel or suppository is inserted.
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The insert will be removed 12 hours after it was inserted or when active labor begins.
How to Store and Dispose of This Medicine:
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If you use this medicine at home, store the insert or suppository in a freezer, away from heat and light until you are ready to insert it.
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Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
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Let your doctor know if you are using any other vaginal medicines.
Warnings While Using This Medicine:
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Tell your doctor if you have had any unusual vaginal bleeding, if you have had 6 or more full-term pregnancies, or if you have pelvic inflammatory disease.
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Let your doctor know if you have heart disease, liver disease, kidney problems, asthma, lung disease, or a history of bleeding disorders, diabetes, glaucoma, or seizures.
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If you are breastfeeding, talk to your doctor before using this medicine.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
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Chest pain or tightness
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Fast, slow, or irregular heartbeat
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Labor pains
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Rash or itching
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Trouble breathing or swallowing
If you notice these less serious side effects, talk with your doctor:
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Back pain or stomach pain
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Diarrhea, nausea, or vomiting
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Fever or chills
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Headache
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Warm feeling in the vagina
If you notice other side effects that you think are caused by this medicine, tell your doctor.
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