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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Hydralazine Hydrochloride (Oral)

Hydralazine Hydrochloride (By Mouth)

Hydralazine Hydrochloride (hye-DRAL-a-zeen hye-droe-KLOR-ide)

Treats high blood pressure and heart failure. Belongs to a class of drugs called vasodilators.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to hydralazine.

How to Use This Medicine:


  • Your doctor will tell you how much to take and how often.
  • Take this medicine exactly as your doctor ordered. Even if you feel fine your blood pressure can still be high.
  • It is best to take your medicine on an empty stomach, 1 hour before or 2 hours after meals.

If a dose is missed:

  • Take the missed dose as soon as you remember.
  • Skip the missed dose if it is almost time for your next regular dose and return to your regular dosing schedule.
  • You should not use two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store at room temperature, away from heat, moisture, and direct light.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are taking diazoxide (Proglycem®), or MAO inhibitors such as Nardil®, Parnate®, or Marplan®.
Warnings While Using This Medicine:

  • Check with your doctor before taking if you have heart or kidney disease, asthma, lupus or if you have had a stroke.
  • Talk with your doctor before use if you are pregnant or breastfeeding.
  • Hydralazine can make some people dizzy or drowsy, be careful if you drive a car or operate machinery.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Chest pain
  • Trouble breathing
  • Skin rash, blisters, severe itching or hives
  • Fever, chills, or sore throat
  • Unusual bruising or bleeding
  • Joint pain
  • Swelling of the feet or legs

If you notice these less serious side effects, talk with your doctor:

  • Headache, dizziness, or lightheadedness
  • Fast heartbeat
  • Numbness or tingling in the hands or feet
  • Appetite loss, nausea, or vomiting
  • Diarrhea or constipation
  • Stuffy nose or watery eyes
  • Facial flushing (redness)
If you notice other side effects that you think are caused by this medicine, tell your doctor.

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