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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Nystatin (Topical)

Nystatin (On The Skin)

Nystatin (nye-STA-tin)

Treats infections caused by fungus. Belongs to a class of drugs called antifungals.

Brand Name(s):

Nystop, Pedi-Dri, Mycostatin
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medication if you have ever had an allergic reaction to nystatin.

How to Use This Medicine:

Cream, Powder, Ointment

  • Your doctor will tell you how much to use and how often.
  • Wash your hands before and after using this medicine.
  • Use this medicine on your skin only. Do not get the medicine in your eyes.
  • Put the medicine on the affected area and rub in gently.
  • Do not put a bandage on the area unless your doctor tells you to. Avoid tight-fitting diapers and plastic pants if using on diaper area of children.
  • It is important to use this medicine for as long as your doctor tells you to.
  • If your infection does not begin to clear after a few days of using this medicine, call your doctor.
  • If using nystatin for an infection of the feet, apply the powder to the affected area and sprinkle it in your socks and shoes as well.

If a dose is missed:

  • Apply the missed dose as soon as possible unless it is almost time for next dose.
  • If it is almost time for your next regular dose, wait until then to use your medicine and skip the missed dose.
  • Do not apply two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store away from heat, moisture, and direct light. Do not freeze.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows before you use any other skin medicine (prescription or nonprescription) on the same area you are treating with nystatin.
Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk with your doctor before using nystatin.
Possible Side Effects While Using This Medicine:

If you notice these less serious side effects, talk with your doctor:

  • Mild stinging or burning where you use the medicine
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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