Oxaprozin (By Mouth)

Oxaprozin (ox-a-PROE-zin)

Treats pain caused by arthritis. Belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs)

Brand Name(s):

Daypro
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to oxaprozin, aspirin, or any pain and arthritis medicines such as Motrin®, Indocin®, Naprosyn® or Aleve®, Tolectin®, or Clinoril®. The reaction may have included wheezing or trouble breathing, hives, rash, or swelling in the face.

How to Use This Medicine:

Tablet

• Your doctor will tell you how much of this medicine to take and how often.
• Take the medicine with a full glass of water.
• You may take the medicine with food, milk, or antacids (such as Maalox® or Mylanta®) so it does not upset your stomach.

If a dose is missed:

• Take the medicine as soon as you remember, unless it is almost time for your next dose.
• Skip the missed dose if it is almost time for your next regular dose.
• You should not use two doses at the same time.

How to Store and Dispose of This Medicine:

• Store at room temperature, away from heat, moisture, and direct light.
• Keep all medicine out of the reach of children.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Avoid drinking alcohol while taking this medicine.
• Make sure your doctor knows if you are taking aspirin, blood thinners such as Coumadin®, or medicines called beta blockers (such as Inderal® and Lopressor®).

Warnings While Using This Medicine:

• Check with your doctor before taking oxaprozin if you have liver or kidney disease, high blood pressure, heart failure, blood disorders, or ulcers or other stomach problems.
• If you are pregnant or breastfeeding, talk to your doctor before taking oxaprozin.
• Ulcers and stomach bleeding are sometimes caused by this type of medicine. These problems can occur without warning signs. You may need to see your doctor for regular check-ups while taking this medicine.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Severe rash, hives, or itching
• Wheezing or trouble breathing
• Swelling in the face or around eyes
• Sudden decrease in amount of urine
• Bloody or black tarry stools
• Severe stomach pain or bloody vomit
• Bloody or cloudy urine
• Unusual bruising or bleeding
• Unexplained fever or sore throat
• Yellowing of skin or eyes

If you notice these less serious side effects, talk with your doctor:

• Nausea
• Upset stomach
• Poor appetite
• Diarrhea
• Mild rash
• Constipation (trouble having a bowel movement)
• Sensitivity of skin to sunlight (use sunscreens)

If you notice other side effects that you think are caused by this medicine, tell your doctor.