Propylthiouracil (Oral) - Drugs Information, Side Effects, & Interactions

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Propylthiouracil (proe-pil-thye-oh-YOOR-a-sil)

Treats hyperthyroidism (too much thyroid hormone produced by the thyroid gland). Also called: PTU

There may be other brand names for this medicine.

You should not use this medicine if you have had an allergic reaction to propylthiouracil or if you are breastfeeding.

Tablet

Your doctor will tell you how much to use and how often. You should not use more of this medicine than your doctor ordered.
It is best to take propylthiouracil at the same time each day. If you take more than one tablet every day, try to take the medicine at evenly spaced intervals, such as every 12 hours if you take it two times a day, or every 8 hours if you take it three times a day.

If a dose is missed:

Use your medicine as soon you remember that you missed a dose.
If it is almost time for your next dose, use two doses together, then go back to your regular schedule.
If you miss more than one dose, check with your doctor.

Store the tablets at room temperature in a closed container, away from heat, moisture, and direct light.
Keep all medicine out of the reach of children.

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Make sure your doctor knows if you are also using amiodarone (Cordarone®), potassium supplements, blood thinners (such as Coumadin®), or digoxin (Lanoxin®).
Talk to your doctor before getting any vaccines (such as flu shots). Also, other people living in your home should not get oral polio vaccine while you are using this medicine. There is a chance they could pass on the polio virus to you.

If you are pregnant, talk to your doctor before using this medicine.
Make sure your doctor knows if you have liver disease before using propylthiouracil.
It may take several days or weeks for propylthiouracil to start working. Do not stop using the medicine without first asking your doctor.
Your doctor will need to check you at regular visits to make sure this medicine is working properly. Keep all your appointments.

Call your doctor right away if you notice any of these side effects:

If you notice these less serious side effects, talk with your doctor:

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