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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Trimipramine Maleate (Oral)

Trimipramine Maleate (By Mouth)

Trimipramine Maleate (trye-MI-pra-meen MAL-ee-ate)

Treats depression. Belongs to a class of drugs called tricyclic antidepressants.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to trimipramine or any other tricyclic antidepressant (such as Elavil®, Anafranil®, or Sinequan®). You should not take trimipramine if you have had a recent heart attack or have taken an MAO inhibitor drug (such as Parnate®, Nardil®, Marplan®) within the past 14 days.

How to Use This Medicine:

Tablet, Capsule

  • Your doctor will tell you how much medicine to take and how often.
  • If you are taking trimipramine for depression, it may be several weeks before you feel better.

If a dose is missed:

  • Take the missed dose as soon as possible.
  • If it is almost time for your next regular dose, wait until then to take your medicine and skip the missed dose.
  • You should not use two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store at room temperature in a closed container, away from heat, moisture, and direct light.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not drink alcohol while taking this medicine.
  • Make sure your doctor knows if you are taking cimetidine (Tagamet®) or any medicines that could make you sleepy such as sleeping pills, cold and allergy pills, other medicine for depression, tranquilizers, antihistamines, and strong pain killers.
Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk your doctor before taking this medicine.
  • Be sure your doctor knows if you have heart or liver disease, seizures, glaucoma, thyroid problems, or problems with urination.
  • Trimipramine may make you sleepy or dizzy. Be careful if driving a car or using machinery.
  • This medicine may make your skin more sensitive to sunlight. Use a sunscreen when out doors. Avoid tanning beds and sunlamps.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Severe confusion or hallucinations
  • Unexplained fever, chills, or sore throat
  • Yellow skin or eyes
  • Hives, rash, or swelling of face, lips, or tongue
  • Difficulty going to the bathroom (urinating)
  • Extreme excitement or irritability

If you notice these less serious side effects, talk with your doctor:

  • Drowsiness or dizziness
  • Headache
  • Dry mouth or blurred vision that does not go away after a few days
  • Trembling or shakiness
  • Nausea
  • Weight gain
If you notice other side effects that you think are caused by this medicine, tell your doctor.

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