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Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
Using advanced liquid chromatography and mass spectrometry techniques coupled with machine learning computer algorithms, researchers have identified 16 metabolite compounds that provided unprecedented accuracy in distinguishing 46 women with early-stage ovarian cancer from a control group of 49 women who did not have the disease. Blood samples for the study were collected from a broad geographic area - Canada, Philadelphia and Atlanta.
While the set of biomarkers reported in this study are the most accurate reported thus far for early-stage ovarian cancer, more extensive testing across a larger population will be needed to determine if the high diagnostic accuracy will be maintained across a larger group of women representing a diversity of ethnic and racial groups.
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$alt_texts= array ('Benign prostatic hyperplasia, or BPH for short, is the enlargement of the prostate gland. It is caused by excess growth of cells in the prostate. This condition is not the same as prostate cancer','Alternate Names : Dysmenorrhea. Menstrual cramps are the pain and cramping some women experience during their monthly periods. The term dysmenorrhea usually refers to pain and cramps severe enough to prevent normal activity','An ectopic pregnancy occurs when a fertilized egg implants outside of the uterus. The most common site is within a fallopian tube. More rarely an embryo may implant within an ovary, in the cervix, or on the abdominal wall','Pregnancy is the period from conception to birth. A pregnancy may be complicated by health problems or lifestyle issues known as risk factors. These risk factors can affect the mother or fetus, or both','Topiramate (toe-PYRE-a-mate) is used to help control some types of seizures in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to help control seizures for as long as you continue to take it.','Irritable bowel syndrome, or IBS, is a condition characterized by abdominal cramping, bloating, gas, and other changes in the bowels','Depression is a medical condition that leads to intense feelings of sadness or despair. These feelings don\'t go away on their own. They are not necessarily related to a particular life event','Tacrolimus ( ta-KROE-li-mus) ointment is used for moderate to severe atopic dermatitis. This is a skin condition where there is itching, redness and inflammation, much like an allergic reaction','Type 2 diabetes mellitus, more often known as type 2 diabetes, is the most common type of diabetes','Personality disorders are chronic mental disorders','Presbyopia is an eye condition in which the lens loses the ability to focus over time');
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