Alosetron (Systemic)
Brand Names : Lotronex
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For alosetron, the following
should be considered:
Allergies - Tell your doctor if you have ever had any unusual
or allergic reaction to alosetron. Also, tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Alosetron has not been studied in pregnant women.
However, alosetron has not been shown to cause birth defects or other problems
in animal studies.
Breast-feeding - It is not known whether alosetron passes into
human breast milk. Although most medicines pass into breast milk in small
amounts, many of them may be used safely while breast-feeding. Mothers who
are taking this medicine and who wish to breast-feed should discuss this with
their doctor.
Children - Studies on this medicine have been done only in
adult patients, and there is no specific information comparing use of alosetron
in children with use in other age groups.
Older adults - Older adults or adults weak from an illness may
be especially sensitive to the effects of alosetron. This may increase the
chance of serious constipation problems.
Other medical problems - The presence of other medical problems may
affect the use of this medicine. Make sure you tell your doctor if you have
any other medical problems, especially:
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Constipation or
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Crohn's disease or
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Diverticulitis or
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Excessive blood clotting problems or
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Intestinal blood circulation problems or
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Intestinal adhesions, obstructions, perforations, or strictures or
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Ischemic colitis or
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Thrombophlebitis or
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Toxic megacolon or
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Ulcerative colitis
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