Antidepressants, Tricyclic (Systemic)
Precautions While Using This Medicine
very important that your doctor check your progress at regular visits to allow
dosage adjustments and to help reduce side effects.
This medicine will add to the effects of alcohol and other CNS depressants
(medicines that make you drowsy or less alert). Some examples of CNS depressants
are antihistamines or medicine for hay fever, other allergies, or colds; sedatives,
tranquilizers, or sleeping medicine; prescription pain medicine or narcotics;
barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including
some dental anesthetics. Check with your medical doctor
or dentist before taking any of the above while you are taking this medicine
This medicine may cause some people to become drowsy. If this occurs, do not drive, use machines, or do anything else that could
be dangerous if you are not alert
Dizziness, lightheadedness, or fainting may occur
especially when you get up from a lying or sitting position. Getting up slowly
may help. If this problem continues or gets worse, check with your doctor.
This medicine may cause dryness of the mouth. For temporary
relief, use sugarless gum or candy, melt bits of ice in your mouth, or use
a saliva substitute
. However, if your mouth continues to feel dry for
more than 2 weeks, check with your medical doctor or dentist. Continuing dryness
of the mouth may increase the chance of dental disease, including tooth decay,
gum disease, and fungus infections.
Tricyclic antidepressants may cause your skin to be more sensitive to sunlight
than it is normally. Exposure to sunlight, even for brief periods of time,
may cause a skin rash, itching, redness or other discoloration of the skin,
or a severe sunburn. When you begin taking this medicine:
Stay out of direct sunlight, especially between the hours of 10:00
a.m. and 3:00 p.m., if possible.
Wear protective clothing, including a hat. Also, wear sunglasses.
Apply a sun block product that has a skin protection factor (SPF)
of at least 15. Some patients may require a product with a higher SPF number,
especially if they have a fair complexion. If you have any questions about
this, check with your health care professional.
Apply a sun block lipstick that has an SPF of at least 15 to protect
Do not use a sunlamp or tanning bed or booth.
If you have a severe reaction from the sun, check with
Before you have any medical tests, tell the medical doctor in charge that
you are taking this medicine. The results of the metyrapone test may be affected
by this medicine.
Before having any kind of surgery, dental treatment,
or emergency treatment, tell the medical doctor or dentist in charge that
you are using this medicine
. Taking tricyclic antidepressants together
with medicines used during surgery or dental or emergency treatments may increase
the risk of side effects.
For diabetic patients
This medicine may affect blood sugar levels. If you notice a change
in the results of your blood or urine sugar tests or if you have any questions,
check with your doctor.
Do not stop taking this medicine without first checking
with your doctor
. Your doctor may want you to reduce gradually the
amount you are using before stopping completely. This may help prevent a possible
worsening of your condition and reduce the possibility of withdrawal symptoms
such as headache, nausea, and/or an overall feeling of discomfort.
The effects of this medicine may last for 3 to 7 days
after you have stopped taking it
. Therefore, all the precautions stated
here must be observed during this time.
For patients taking protriptyline
If taken late in the day, protriptyline may interfere with nighttime