Danaparoid (Systemic)

Brand Names : Orgaran

Before Using This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For danaparoid, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to danaparoid or heparin. Also tell your health care professional if you are allergic to any other substances, such as foods, especially pork or pork products, preservatives, or dyes.

Pregnancy - Danaparoid has not been studied in pregnant women. However, it has not been found to cause birth defects in animals.

Breast-feeding - It is not known whether this medicine passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are using this medicine and who wish to breast-feed should discuss this with their doctor.

Children - Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of danaparoid in children with use in other age groups.

Older adults - Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of danaparoid in the elderly with use in other age groups.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems - The presence of other medical problems may affect the use of danaparoid. Make sure you tell your doctor if you have any other medical problems, especially:

• Bleeding problems or
• Heart infection or
• High blood pressure (hypertension) or
• Kidney disease or
• Stomach or intestinal ulcer (active) or
• Stroke - The risk of bleeding may be increased

Also, tell your doctor if you have received danaparoid before and had a reaction to it called thrombocytopenia (a low platelet count in the blood), or if new blood clots formed while you were receiving the medicine.

In addition, tell your doctor if you have recently had medical surgery . This may increase the risk of serious bleeding when you are taking danaparoid.