Dapsone (Systemic)

Brand Names : Avlosulfon, DDS

Proper Use of This Medicine

For patients taking dapsone for leprosy:

• To help clear up your leprosy completely or to keep it from coming back, it is very important that you keep taking this medicine for the full time of treatment , even if you begin to feel better after a few weeks or months. You may have to take it every day for as long as 3 years or more, or for life. If you stop taking this medicine too soon, your symptoms may return.
• This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take each dose at the same time every day . If you need help in planning the best time to take your medicine, check with your health care professional.

For patients taking dapsone for dermatitis herpetiformis:

• Your doctor may want you to follow a gluten-free diet. If you have any questions about this, check with your doctor.

Dosing - The dose of dapsone will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of dapsone. If your dose is different, do not change it unless your doctor tells you to do so.

The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking dapsone .

• For oral dosage form (tablets):
  • For Hansen's disease (leprosy):
    • Adults and teenagers - 50 to 100 milligrams (mg) once a day; or 1.4 mg per kilogram (kg) (0.6 mg per pound) of body weight once a day. Dapsone should be taken with other medicines to treat Hansen's disease.
    • Children - Dose is based on body weight. The usual dose is 1.4 mg per kg (0.6 mg per pound) of body weight once a day. Dapsone should be taken with other medicines to treat Hansen's disease.
  • For dermatitis herpetiformis:
    • Adults and teenagers - 50 mg once a day to start. Your doctor will increase your dose, up to 300 mg once a day, until your symptoms are controlled. Then your dose will be decreased to the lowest dose that will still control your symptoms.
    • Children - Dose is based on body weight. The usual dose is 2 mg per kg (0.9 mg per pound) of body weight once a day to start. Your doctor will increase your dose until your symptoms are controlled. Then your dose will be decreased to the lowest dose that will still control your symptoms.

Missed dose - You may skip a missed dose if it does not make your symptoms come back or get worse. If your symptoms do come back or get worse, take the missed dose as soon as possible. Then go back to your regular dosing schedule.

Storage - To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.