Dolasetron (Systemic)

Brand Names : Anzemet

Proper Use of This Medicine

Dosing - The dose of dolasetron will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of dolasetron. If your dose is different, do not change it unless your doctor tells you to do so.

The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking dolasetron .

• For oral dosage form (tablets):
  • For prevention of nausea and vomiting after anticancer medicine:
    • Adults - 100 milligrams (mg) given within one hour before the anticancer medicine is given.
    • Children 2 to 16 years of age - 1.8 mg per kilogram (kg) (0.82 mg per pound) of body weight given within one hour before the anticancer medicine is given. The dose generally is not greater than 100 mg.
    • Children up to 2 years of age - Use and dose must be determined by your doctor.
  • For prevention of nausea and vomiting after surgery:
    • Adults - 100 mg given within two hours before surgery.
    • Children 2 to 16 years of age - 1.2 mg per kg (0.55 mg per pound) of body weight given within two hours before surgery. The dose generally is not greater than 100 mg.
    • Children up to 2 years of age - Use and dose must be determined by your doctor.
• For injection dosage form:
  • For prevention of nausea and vomiting after anticancer medicine:
    • Adults - 100 milligrams (mg) given into a vein approximately 30 minutes before the anticancer medicine is given.
    • Children 2 to 16 years of age - 1.8 mg per kilogram (kg) (0.82 mg per pound) of body weight given into a vein approximately 30 minutes before the anticancer medicine is given. The dose generally is not greater than 100 mg.
    • Children up to 2 years of age - Use and dose must be determined by your doctor.
  • For prevention of nausea and vomiting after surgery:
    • Adults - 12.5 mg given into a vein approximately 15 minutes before anesthesia (medicine to put you to sleep during surgery) is ended.
    • Children 2 to 16 years of age - 0.35 mg per kg (0.16 mg per pound) of body weight given into a vein approximately 15 minutes before anesthesia (medicine to put you to sleep during surgery) is ended. The dose generally is not greater than 12.5 mg.
    • Children up to 2 years of age - Use and dose must be determined by your doctor.
  • For treatment of nausea and vomiting after surgery:
    • Adults - 12.5 mg given into a vein as soon as nausea and vomiting start.
    • Children 2 to 16 years of age - 0.35 mg per kg (0.16 mg per pound) of body weight given into a vein as soon as nausea and vomiting start. The dose generally is not greater than 12.5 mg.
    • Children up to 2 years of age - Use and dose must be determined by your doctor.

Storage - To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Keep the medicine from freezing. Do not refrigerate.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.