Entacapone (Systemic)

Brand Names : Comtan

Proper Use of This Medicine

Take this medicine only as directed by your doctor, to help your condition as much as possible. Do not take more or less of it, and do not take it more or less often than your doctor ordered.

Dosing - The dose of entacapone will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of entacapone. If your dose is different, do not change it unless your doctor tells you to do so.

Entacapone is always used in combination with levodopa/carbidopa (Sinemet); never alone.

The number of times a day you take the tablets depends on how often you take levodopa/carbidopa (Sinemet).

• For oral dosage form (tablets):
  • For Parkinson's disease:
    • Adults - 200 mg with each levodopa/carbidopa (Sinemet) dose. Entacapone may be taken up to 8 times a day, but the total daily dose is usually not more than 1600 mg..
    • Children - Use and dose must be determined by your doctor.

Missed dose - Always take with your levodopa/carbidopa (Sinemet). If you miss a dose of this medicine, take it as soon as possible. However, if your next scheduled dose is within 2 hours, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage - To store this medicine:

• Keep out of the reach of children.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Ask your health care professional how you should dispose of any medicine you do not use. Be sure that any discarded medicine is out of the reach of children.