Mexiletine (Systemic)
Brand Names : Mexitil
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For mexiletine, the
following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to mexiletine, lidocaine, or tocainide. Also tell your health
care professional if you are allergic to any other substance, such as foods,
preservatives, or dyes.
Pregnancy - Mexiletine has not been studied in pregnant women.
However, studies in animals have shown that mexiletine causes a decrease in
successful pregnancies but no birth defects. Before taking this medicine,
make sure your doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding - Mexiletine passes into breast milk. Because this
medicine may cause serious side effects, breast-feeding is generally not recommended
while you are receiving it. Be sure you have discussed this with your doctor
before taking mexiletine.
Children - Studies on this medicine have been done only in adult
patients, and there is no specific information comparing use of mexiletine
in children with use in other age groups.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults or if they cause different side effects
or problems in older people. There is no specific information comparing use
of mexiletine in the elderly with use in other age groups.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. Tell your health care
professional if you are taking any other prescription or nonprescription (over-the-counter
[OTC]) medicine.
Smoking - Smoking may decrease the effects of mexiletine.
Other medical problems - The presence of other medical problems may affect
the use of mexiletine. Make sure you tell your doctor if you have any other
medical problems, especially:
-
Congestive heart failure or
-
Low blood pressure - Mexiletine may make these conditions worse
-
Heart attack (severe) or
-
Liver disease - Effects may last longer because of slower removal
of mexiletine from the body
-
Seizures (history of) - Mexiletine can cause seizures
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