Rifabutin (Systemic)
Brand Names : Mycobutin
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For rifabutin, the following
should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to rifabutin or rifampin. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Rifabutin has not been studied in pregnant women.
However, studies in animals have shown that rifabutin causes birth defects.
Before you take this medicine, make sure your doctor knows if you are pregnant
or if you may become pregnant.
Breast-feeding - It is not known whether rifabutin passes into the
breast milk. However, if your baby does not have the AIDS virus, there is
a chance that you could pass the virus to your baby by breast-feeding. Talk
to your doctor first if you are thinking about breast-feeding your baby.
Children - Studies on this medicine have only been done in adult
patients, and there is no specific information comparing use of rifabutin
in children with use in other age groups. However, studies are being done
to determine the best dose for children.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults. Although there is no specific information
comparing use of rifabutin in the elderly with use in other age groups, this
medicine is not expected to cause different side effects or problems in older
people than it does in younger adults.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
rifabutin, it is especially important that your health care professional know
if you are taking any of the following:
-
Amprenavir (e.g. Agenerase) or
-
Delavirdine (e.g., Rescriptor) or
-
Efavirenz (e.g., Sustiva) or
-
Indinavir (e.g., Crixivan) or
-
Nelfinavir (e.g., Viracept) or
-
Nevirapine (e.g., Viramune) or
-
Ritonavir (e.g., Norvir) or
-
Saquinavir (e.g., Fortovase, Invirase) or
-
Zidovudine (e.g., AZT, Retrovir) - Use of rifabutin with these
medicines may lower the amount of these medicines in the blood
-
Oral contraceptives (birth control pills) containing estrogen - Use
of rifabutin with these birth control pills may increase the chance of pregnancy
occurring
Other medical problems - The presence of other medical
problems may affect the use of rifabutin. Make sure you tell your doctor if
you have any other medical problems especially:
-
Kidney disease, mild to severe
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