Risperidone (Systemic)
Brand Names : Risperdal
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For risperidone, the
following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to risperidone. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Studies with risperidone have not been done in pregnant
women. One baby whose mother took risperidone during pregnancy was born with
a serious brain problem. However, it is not known whether this problem was
caused by risperidone. Some unwanted effects have been reported in animal
studies, but the risk to human babies is not clear. Before taking this medicine,
make sure your doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding - Risperidone passes into human milk and may cause
unwanted effects, such as behavior changes, in nursing babies. It may be necessary
for you to take another medicine or to stop breast-feeding during treatment.
Be sure you have discussed the risks and benefits of the medicine with your
doctor.
Children - Studies on this medicine have been done only in adult
patients, and there is no specific information comparing use of risperidone
in children with use in other age groups.
Older adults - Elderly people may be especially sensitive to the
effects of risperidone. This may increase the chance of having side effects
during treatment.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
risperidone, it is especially important that your health care professional
know if you are taking any of the following:
-
Amiodarone [e.g., Cordarone] or
-
Amitriptyline [e.g., Elavil] or
-
Arsenic trioxide [e.g., Trisenox] or
-
Bepridil [e.g., Vascor] or
-
Chlorpromazine [e.g., Thorazine] or
-
Cisapride [e.g., Propulsid] or
-
Clarithromycin [e.g., Biaxin] or
-
Clomipramine [e.g., Anafranil] or
-
Clozapine [e.g., Clozaril] or
-
Desipramine [e.g., Norpramin] or
-
Disopyramide [e.g., Norpace] or
-
Dofetilide [e.g., Tikosyn] or
-
Dolasetron [e.g., Anzemet] or
-
Droperidol [e.g., Inapsine] or
-
Erythromycin [e.g., E-mycin] or
-
Gatifloxacin [e.g., Tequin] or
-
Halofantrin [e.g., Halfan] or
-
Haloperidol [e.g., Haldol] or
-
Ibutilide intravenous injection [e.g., Covert] or
-
Levofloxacin [e.g., Leaquin] or
-
Levomethadyl [e.g., Orlaam] or
-
Mefloquine [e.g., Lariam] or
-
Mesoridazine [e.g., Serentil] or
-
Moxifloxacin [e.g., Avelox] or
-
Ondansetron [e.g., Zofran] or
-
Pimozide [e.g., Orap] or
-
Procainamide [e.g., Procainbid, Pronestyl] or
-
Propafenone [e.g., Rythmol] or
-
Quinidine [e.g., Quinaglute, Quinidex] or
-
Sotalol [e.g., Betapace, Sorine] or
-
Sumatriptan [e.g., Imitrex] or
-
Thioridazine [e.g., Mellaril] or
-
Ziprasidone [e.g., Geodon] or
-
Zolmitriptan [e.g., Zomig] - These medicines may increase the
chance of serious side effects and should not be taken with risperidone
-
Alcohol or
-
Antihypertensives (high blood pressure medicine) or
-
Central nervous system (CNS) depressants (medicine that makes you
drowsy or less alert) or
-
Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine
[e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Norpramin],
doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g.,
Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil]) - Risperidone
may add to the effects of these medicines, causing unwanted effects such as
increased drowsiness or low blood pressure
-
Bromocriptine (e.g., Parlodel) or
-
Levodopa (e.g., Larodopa, Sinemet) or
-
Pergolide (e.g., Permax) - Risperidone may interfere with the
effects of these medicines so that they do not work properly
-
Carbamazepine (e.g., Epitol, Tegretol) or
-
Clozapine (e.g., Clozaril) or
-
Fluoxetine (e.g., Prozac, Sarafem) - These medicines may affect
the blood levels of risperidone so that risperidone does not work properly
or causes unwanted effects. Your doctor may need to change your dose of risperidone
Other medical problems - The presence of other medical
problems may affect the use of risperidone. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Breast cancer or
-
Heart or blood vessel problems, including stroke and unusual heartbeats
or
-
Parkinson's disease - Risperidone may make these conditions worse
-
Dehydration or
-
Blood circulation problems - These conditions may increase the
chance of side effects from the medicine
-
Dementia, such as decreasing mental ability or
-
Difficulty swallowing - These conditions may increase the chance
of side effects from the medicine
-
Epilepsy or other seizure disorders - Risperidone may increase
the risk of having seizures
-
Kidney disease or
-
Liver disease - Higher blood levels of risperidone may occur,
increasing the chance of side effects
-
Other medical problems causing vomiting [e.g., brain tumor, bowel
blockage, drug overdose, Reye's syndrome] - Risperidone may prevent vomiting
and hide these medical problems from you and your doctor
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