Sirolimus (Systemic)
Brand Names : rapamycin, Rapamune
Precautions While Using This MedicineIt is very important that your doctor check your progress
at regular visits
to make sure that this medicine is working properly
and to check for unwanted effects.
While you are taking sirolimus, it is important to maintain good dental
hygiene and see a dentist regularly for teeth cleaning.
Raw oysters or other shellfish may contain bacteria
that can cause serious illness and possibly death. This is more likely to
be a problem if these foods are eaten by patients with certain medical conditions.
Even eating oysters from �clean� water or good restaurants
does not guarantee that the oysters do not contain the bacteria. Eating raw
shellfish is not a problem for most healthy people; however, patients with
the following conditions may be at greater risk: cancer, immune disorders,
organ transplantation, long-term corticosteroid use (as for asthma, arthritis,
or organ transplantation), liver disease (including viral hepatitis), excess
alcohol intake (2 to 3 drinks or more per day), diabetes, stomach problems
(including stomach surgery and low stomach acid), and hemochromatosis (an
iron disorder). Do not eat raw oysters or other shellfish
while you are taking sirolimus. Be sure oysters and shellfish are fully cooked.
While you are being treated with sirolimus, and after you stop treatment
with it, it is important to see your doctor about the
immunizations (vaccinations) you should receive. Do not get any immunizations
without your doctor's approval.
Sirolimus may lower your body's resistance
and there is a chance you might get the infection the immunization is meant
to prevent. In addition, other persons living in your household should not
take or have recently taken oral polio vaccine since there is a chance they
could pass the polio virus on to you. Also, avoid other persons who have taken
the oral polio vaccine. Do not get close to them, and do not stay in the same
room with them for very long. If you cannot take these precautions, you should
consider wearing a protective face mask that covers the nose and mouth.
Treatment with sirolimus may also increase the chance of getting other
infections. If you can, avoid people with colds or other infections. If you
think you are getting a cold or other infection, check with your doctor.
Grapefruits and grapefruit juice may increase the effects of sirolimus
by increasing the amount of this medicine in your body. You should not eat grapefruit or drink grapefruit juice while you taking this
medicine.
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