Vigabatrin (Systemic)
Brand Names : Sabril
Before Using This MedicineIn deciding
to use a medicine, the risks of taking vigabatrin must be weighed against
the good it will do. This is a decision you and your doctor will make. For
vigabatrin, the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual
or allergic reaction to vigabatrin. Also tell your health care provider if
you are allergic to any other substances, such as foods, preservatives, or
dyes.
Pregnancy - Studies have not been done in pregnant women.
However, studies in rabbits have shown that vigabatrin causes birth defects.
Before taking this medicine, make sure your doctor knows if you are pregnant
or if you may become pregnant.
Breast-feeding - It is not known if vigabatrin passes into breast
milk. Because of the risk of unwanted effects in the nursing infant, breast-feeding
is not recommended.
Children - This medicine has been tested in children and,
in effective doses, has not been shown to cause different problems than it
does in adults.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults or if they cause different side effects
or problems in older people. There is no specific information comparing use
of vigabatrin in the elderly with use in other age groups.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. Tell your health care
professional if you are using any other prescription or nonprescription (over-the-counter
[OTC]) medicine.
Other medical problems - The presence of other medical
problems may affect the use of vigabatrin. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Mental illness - Patients with a history of emotional or behavioral
disturbances may be more likely to have an episode following vigabatrin therapy.
-
Kidney disease - Vigabatrin is removed from the body by the
kidney; slower removal from the body may increase the chance of side effects
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