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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Anti-Inhibitor Coagulant Complex (Injection)

Anti-Inhibitor Coagulant Complex (Injection)

Anti-Inhibitor Coagulant Complex (AN-tee in-HIB-i-ter co-AG-yoo-lant kom-plex)

Controls bleeding in patients who have hemophilia A or hemophilia B, disorders in which blood does not form clots normally.

Brand Name(s):

Autoplex T, Feiba-VH Immuno
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not get this medicine if you have had an allergic reaction to anti-inhibitor coagulant complex.

How to Use This Medicine:


  • Your doctor will prescribe your dose and tell you how often to use the medicine.
  • Before you give the medicine, look at the liquid in the bag or syringe, if you see specks or solid pieces, You should not use the medicine. Mix a new dose of the medicine.
  • After it is mixed, give the medicine right away. The treatment needs to be done within 1 hour after mixing (if you are using Autoplex®) or within 3 hours (if you are using FEIBA®).
  • The medicine is given directly into a blood vein. This is called intravenous, or IV.
  • The medicine must be given by someone trained to give an IV, such as a nurse. You, someone in your family, or a friend can also be taught to give the medicine.
  • The medicine needs to be mixed with liquid (sterile water) before it is given. When it is time for your treatment, bring the medicine and sterile water to room temperature. Make sure you understand how to mix the powder with the water before giving your treatment.
  • If the medicine goes into your veins too fast, it can cause headaches, flushing, or changes in blood pressure and heartbeat. The symptoms will usually go away if you stop the treatment. You may need to give the medicine more slowly. Talk to your caregiver about this.

If a dose is missed:

  • If possible, have someone in your family or a friend trained to give your treatment in case you cannot give it to yourself.
  • If you do miss a dose, ask your doctor or home health caregiver for instructions.
How to Store and Dispose of This Medicine:

  • Keep the bottles of powder and liquid in the refrigerator. Do not freeze.
  • Do not put the mixed medicine in the refrigerator.
  • Keep all medicine out of the reach of children.
  • If you give your own treatments, your should be given a special container for the used needles, syringes or tubes. Keep it where children or pets cannot reach it.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Patients who have hemophilia should not take aspirin, because it may increase bleeding.
Warnings While Using This Medicine:

  • Check with your doctor before using the medicine if you have liver disease or if you are pregnant or breastfeeding.
  • This medicine is taken from human blood that has been tested for viruses and treated to keep from spreading infections. The risk of getting HIV (human immunodeficiency virus, the virus that causes AIDS) or hepatitis from this medicine is very low, but cannot be completely eliminated. Your doctor may want you to have a hepatitis B vaccine.
  • If you have fast heartbeat, trouble breathing, chest pain, or coughing during your treatment, stop giving the medicine and tell your doctor or home health caregiver.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Wheezing, trouble breathing, or chest tightness
  • Hives or rash
  • Swelling of the face, around eyes, or mouth
  • Nausea and vomiting
  • Yellowing of skin or eyes
  • Dark-colored urine
  • Fever or chills

If you notice these less serious side effects, talk with your doctor:

  • Headache
  • Back pain
  • Tiredness
If you notice other side effects that you think are caused by this medicine, tell your doctor.

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