3-rx.comCustomer Support
HomeAbout UsFAQContactHelp
News Center
Health Centers
Medical Encyclopedia
Drugs & Medications
Diseases & Conditions
Medical Symptoms
Med. Tests & Exams
Surgery & Procedures
Injuries & Wounds
Diet & Nutrition
Special Topics

\"$alt_text\"');"); } else { echo"\"$alt_text\""; } ?>

Join our Mailing List


You are here : 3-RX.com > Home > Heart -

Sleep apnea in middle age raises heart disease risk

HeartAug 30, 06

Obstructive sleep apnea in middle-aged adults may increase the risk of coronary artery disease by up to five-fold, research in Sweden suggests. However, successful treatment of the sleep apnea significantly cuts that risk.

Although evidence supports ties between sleep apnea—that is, brief but frequent episodes during the night when breathing becomes blocked—and coronary artery disease, a causal relationship has not been established, Dr. Yuksel Peker and his colleagues at Sahlgrenska University Hospital in Goteborg note. The concomitant presence of other illnesses further complicates the ability to delineate cause and effect.

For their study, Peker’s team identified 308 middle-age individuals (ages 30 to 69 years) who had been evaluated for obstructive sleep apnea in 1991 and were free of any heart disease at baseline. Nearly one-third (n=105) patients had documented obstructive sleep apnea.

Patients were offered various standard treatments including CPAP (continuous positive airway pressure), surgery, or an oral appliance. Sleep apnea was not resolved despite treatment or offers of treatment in 65 patients.

Over the next 7 years, coronary artery disease was diagnosed in 16.2 percent of patients with sleep apnea and 5.4 percent of those without apnea. Eight deaths due to coronary artery disease occurred in the apnea group and one in the non-apnea group.

Among patients with ineffective treatment, coronary artery disease was diagnosed in 24.6 percent versus 3.9 percent of those effectively treated.

In “multivariate analysis,” obstructive sleep apnea at baseline nearly quintupled the risk of developing coronary artery disease, the investigators report, regardless of age, gender, high blood pressure, diabetes, or current smoking.

However, effective sleep apnea treatment reduced the increased risk by about two thirds.

In the European Respiratory Journal, Peker’s team maintains that their study “clearly suggests a causal relationship between obstructive sleep apnea and coronary artery disease.”

“Even mild obstructive sleep apnea seems to have a substantial effect on coronary artery disease risk, and highly effective treatment should therefore be provided,” they write.

SOURCE: European Respiratory Journal, September 2006.

Print Version
comments powered by Disqus

  New superfoods could help key protein keep bodies healthy
  Mobile app on emergency cardiac care aids best decisions in seconds
  Train your heart to protect your mind
  Mass. General study identifies path to safer drugs for heart disease, cancer
  Tweaking MRI to track creatine may spot heart problems earlier, Penn Medicine study suggests
  Method to estimate LDL-C may provide more accurate risk classification
  Texting heart medication reminders improved patient adherence
  Hybrid heart valve is strong, durable in early tests
  Cardiopoietic ‘Smart’ Stem Cells Show Promise in Heart Failure Patients
  Vitamin D deficiency ups heart disease risk
  Heart surgery safe in Jehovah’s Witnesses
  Magnet helps target transplanted iron-loaded cells to key areas of heart


Home | About Us | FAQ | Contact | Advertising Policy | Privacy Policy | Bookmark Site