Hepatitis A Virus Vaccine Inactivated and Hepatitis B Virus Vaccine Recombinant (Systemic)
Brand Names : Twinrix
A virus vaccine
inactivated and hepatitis B virus vaccine recombinant is used to prevent infection
caused by Hepatitis A and Hepatitis B in patients 18 years of age or older.
The vaccine works by causing your body to produce its own protection (antibodies)
against the disease. Hepatitis A and Hepatitis B are highly contagious, serious
diseases of the liver.
The hepatitis A virus (HAV) is spread most often through infected food
or water. Hepatitis A may also be spread by close person-to-person contact
with infected persons (such as between persons living in the same household).
Although some infected persons do not appear to be sick, they are still able
to spread the virus to others.
Hepatitis A is less common in the U.S. and other areas of the world that
have a higher level of sanitation and good water and sewage (waste) systems.
However, it is a significant health problem in parts of the world that do
not have such systems. If you are traveling to certain countries or remote
(out-of-the-way) areas, hepatitis A vaccine will help protect you from hepatitis
Hepatitis B (HBV) is spread by contact with body fluids, such as blood,
saliva, semen, or vaginal fluids; by needle sticks or sharing needles; or
from mother to child.
Hepatitis A and Hepatitis B combination vaccine is recommended for all
persons 18 years of age or older who are at risk from infection from their
jobs or some behaviors, or from traveling to the following parts of the world:
Central and South America.
Eastern and southern Europe.
the Middle East.
South and southeast Asia (except Japan).
the Soviet Union (former).
Hepatitis A and Hepatitis B combination vaccine is also recommended for:
Persons living in or moving to areas that have a high rate of HAV
infection and who are at a high risk of HBV infection.
Persons engaging in high-risk sexual activity, such as homosexual
and bisexual males.
Persons who use illegal injectable drugs.
Persons at risk through their work, such as laboratory workers who
handle live hepatitis A and hepatitis B virus, police and those who give first
aid or medical help, and workers who come in contact with stool or sewage.
People who work in child day-care centers and correctional facilities,
residents of drug and alcohol treatment centers, and patients and staff in
Patients who frequently receive blood and blood products, including
those people who have problems with clotting, such as hemophiliacs.
Persons with chronic liver disease.
Healthcare workers who give first aid or emergency medical care.
People who are at increased risk for HBV infection and who are in
close contact with patients that have hepatitis A or B.
This medicine is available only with your doctor's prescription, in the
following dosage form:
Some commonly used brand names are:
In the U.S. -