Histrelin (Systemic)

Brand Names : Supprelin

Side Effects of This Medicine

In the first few weeks of therapy, you may notice puberty progressing in your child, including light vaginal bleeding and breast enlargement in girls. Within 4 weeks after histrelin has had time to begin working properly, you should see signs in boys and girls that puberty is stopping.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Bloody mucus in nose or unexplained nosebleeds; convulsion; difficulty in swallowing; feeling of fast or irregular heartbeat; flushing of skin; increased blood pressure; itching or redness of skin; lightheadedness; loss of consciousness; migraine headaches; swelling of skin; trouble in breathing

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Headache; redness, swelling, and itching of skin at place of injection; skin rash; vaginal bleeding (for a short-term, occurring within first 3 weeks of therapy initiation); white vaginal discharge

Less common

Anxiety; blood in urine; breast swelling, pain, or discharge; brownish vaginal discharge with odor; chills; conduct disorder; cough; difficulty in seeing; dizziness; earache; feeling of warmth; frequent urge to urinate; hair loss; increased sensitivity of eyes to light; irritation or itching of vaginal area; loss of appetite; lower back pain; mental depression; nervousness; pain in chest, legs, joints, or neck; pain or burning while urinating; paleness of skin; red or purple spots on skin, varying in size from pinpoint to large bruises; seeing two objects instead of just one; sore throat; sudden sweating; thickened patches of skin; trembling or shaking; unusual tiredness or weakness

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Abdominal pain or cramping; diarrhea; nausea; vomiting

Less common

Constipation; increased appetite; increased thirst

Other side effects not listed above also may occur in some patients. If you notice any other effects, check with your doctor.