Brand Names : Supprelin
- Gonadotropin inhibitor
- gonadotropin-releasing hormone analog
Histrelin (his-TREL-in) is a hormone similar to one normally released
from the hypothalamus gland in the brain. Histrelin is used in the treatment
of central precocious puberty (CPP), a condition that causes early puberty
in boys (before 9.5 years of age) and in girls (before 8 years of age). Histrelin
works by decreasing the amount of estrogen and testosterone in the blood.
When given regularly to boys and girls, this medicine helps to delay early
puberty, slowing down the development of breasts in girls and the development
of genital areas in boys and girls. This medicine delays puberty in a child
only as long as the child continues to receive it.
Suppressing estrogen can cause thinning of the bones or slowing of their
growth. Slowing the growth of bones is a positive effect in girls and boys
whose bones grow too fast when puberty begins too early. Boys and girls may
benefit by adding inches to their adult height when histrelin helps their
bones grow at the proper and expected rate for children.
This medicine is available only with your doctor's prescription, in the
following dosage form(s):
Some commonly used brand names are:
In the U.S. -
† Not commercially available in Canada.