Nadroparin (Systemic)

Brand Names : Fraxiparine, Fraxiparine Forte

Before Using This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For nadroparin, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to nadroparin. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Nadroparin has not been shown to cause birth defects or other problems in humans or animals. However, before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant.

Breast-feeding - It is not known whether nadroparin passes into breast milk. However, mothers receiving nadroparin should avoid breast-feeding.

Children - Studies on this medicine have been done only in adult patients and there is no specific information comparing use of nadroparin in children with use in other age groups.

Older adults - This medicine has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking nadroparin, it is especially important that your health care professional know if you are taking any of the following:

• Abciximab (e.g., ReoPro) or
• Anagrelide (e.g., Agrylin) or
• Calcium channel blocking agents (bepridil [e.g., Vascor], diltiazem [e.g., Cardizem], felodipine [e.g., Plendil], flunarizine [e.g., Sibelium], nicardipine [e.g., Cardene], nifedipine [e.g., Procardia], nimodipine [e.g., Nimotop], verapamil [e.g., Calan]) or
• Clopidogril (e.g., Plavix) or
• Dipyridamole (e.g., Persantine) or
• Divalproex (e.g., Depakote) or
• Epoprostenol (e.g., Flolan) or
• Eptifibatide (e.g., Integrilin) or
• Inflammation or pain medicine, except narcotics or
• Mezlocillin (e.g., Mezlin) or
• Pentoxifylline (e.g., Trental) or
• Piperacillin (e.g., Pipracil) or
• Plicamycin (e.g., Mithracin) or
• Sulfinpyrazone (e.g., Anturane) or
• Ticarcillin (e.g., Ticar) or
• Ticlopidine (e.g., Ticlid) or
• Tirofiban (e.g., Aggrastat) or
• Valproic acid (e.g., Depakene) - Using any of these medicines together with nadroparin may increase the risk of bleeding

Other medical problems - The presence of other medical problems may affect the use of nadroparin. Make sure you tell your doctor if you have any other medical problems, especially:

• Abortion (risk of) or
• Bleeding problems or
• Eye problems caused by diabetes or high blood pressure or
• Heart infection or
• High blood pressure or
• Injury or surgery involving the brain, ears, eyes, or spinal cord or
• Liver disease or
• Low blood platelet count or
• Stomach or intestinal ulcer or
• Stroke - The risk of bleeding may be increased

• Kidney disease - Nadroparin is removed from the body by the kidneys; patients with kidney disease may need to receive a lower dose of nadroparin