Nadroparin (Systemic)

Brand Names : Fraxiparine, Fraxiparine Forte

Proper Use of This Medicine

If you are using nadroparin at home, your health care professional will teach you how to inject yourself with the medicine. Be sure to follow the directions carefully. Check with your health care professional if you have any problems using the medicine.

Put used syringes in a puncture-resistant, disposable container or dispose of them as directed by your health care professional.

Dosing - The dose of nadroparin will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of nadroparin. If your dose is different, do not change it unless your doctor tells you to do so.

The number of milliliters (mL) of nadroparin that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking nadroparin:

• For injection dosage form:
  • For unstable angina or certain types of heart attacks:
    • Adults: The dose is based on body weight. It is usually 86 anti-factor Xa International Units (IU) per kilogram (kg) (39.1 anti-factor Xa IU per pound) of body weight injected under the skin every twelve hours for six days.
    • Children: Use and dose must be determined by your doctor.
  • For prevention of deep vein thrombosis (blood clots in the legs) or pulmonary embolism (blood clots in the lungs) after general surgery:
    • Adults: The dose is usually 2850 anti-factor Xa IU injected under the skin once a day beginning two to four hours before surgery and continuing for at least seven days.
    • Children: Use and dose must be determined by your doctor.
  • For prevention of deep vein thrombosis or pulmonary embolism after hip replacement surgery:
    • Adults: The dose is usually 38 anti-factor Xa IU per kg (17.3 anti-factor Xa IU per pound) of body weight injected under the skin twelve hours before surgery, twelve hours after surgery, and once a day for the first three days after surgery. Then, the dose is 57 anti-factor Xa IU per kg (26 anti-factor Xa IU per pound) of body weight injected under the skin once a day from the fourth through the tenth days after surgery.
    • Children: Use and dose must be determined by your doctor.
  • For treatment of deep vein thrombosis:
    • Adults:
      • Patients weighing less than 40 kg (88 pounds) or more than 100 kg (220 pounds): Dose must be determined by your doctor.
      • Patients weighing 40 to 100 kg (88 to 220 pounds): The dose is usually 171 anti-factor Xa IU per kg (77.7 anti-factor Xa IU per pound) of body weight injected under the skin once a day. Or, the dose may be 86 anti-factor Xa IU per kg (39.1 anti-factor Xa IU per pound) of body weight injected under the skin two times a day.
    • Children: Use and dose must be determined by your doctor.
  • For prevention of blood clots during hemodialysis (kidney dialysis):
    • Adults: The dose is usually 65 anti-factor Xa IU per kg (29.5 anti-factor Xa IU per pound) of body weight injected into an artery at the start of each dialysis session.
    • Children: Use and dose must be determined by your doctor.

Storage - To store this medicine:

• Keep out of the reach of children.
• Keep the medicine from freezing. Do not refrigerate.
• Do not keep outdated medicine or medicine no longer needed. Ask your health care professional how you should dispose of any medicine you do not use. Be sure that any discarded medicine is out of the reach of children.