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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Nafarelin

Nafarelin (Systemic)

Brand Names : Synarel

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects

Category
  • Antiendometriotic agent
  • gonadotropin inhibitor
  • gonadotropin-releasing hormone analog
Description

Nafarelin (NAF-a-re-lin) is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used in the treatment of:

  • Endometriosis, a painful condition caused by extra tissue similar to the lining of the uterus growing inside and outside of the uterus.
  • Central precocious puberty (CPP), puberty developing too early in boys and girls.
Nafarelin works by decreasing the amount of estrogen and testosterone in the blood.

When given regularly to boys and girls, this medicine helps to prevent them from continuing to develop the sexual features associated with puberty, slowing down the development of breasts in girls and the development of genital areas in boys and girls. This medicine delays puberty in a child only as long as the child continues to take it.

Nafarelin prevents the growth of tissue associated with endometriosis in adult women during treatment and for 6 months after treatment is discontinued. Reducing the amount of estrogen in the body is one way of treating endometriosis.

Suppressing estrogen can thin the bones or slow their growth. This is a problem for adult women whose bones are no longer growing like the bones of children. Slowing the growth of bones is a positive effect for girls and boys whose bones grow too fast when puberty begins too early. This is why nafarelin is used only for up to 6 months in adult women treated for endometriosis, but often is used for a longer time in girls and boys with pubertal problems. Boys and girls may benefit by adding inches to their adult height when nafarelin causes their bones to grow at a proper rate.

Nafarelin is available only with your doctor's prescription, in the following dosage form:

    Nasal
  • Solution (U.S. and Canada)

Brand Names

Some commonly used brand names are:

In the U.S. -

  • Synarel

In Canada -

  • Synarel

   

Next section

   

Nafarelin: Before Using



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