Phenothiazines (Systemic)
Category- Analgesic - Methotrimeprazine
- Anesthetic adjunct - Chlorpromazine; Methotrimeprazine,
intravenous
- Antidyskinetic, Huntington's chorea - Chlorpromazine; Thioridazine
- Antiemetic - Chlorpromazine; Methotrimeprazine; Perphenazine; Prochlorperazine; Trifluoperazine; Triflupromazine
- Antineuralgia adjunct - Fluphenazine
- Antipsychotic - Chlorpromazine; Fluphenazine; Mesoridazine; Methotrimeprazine; Perphenazine; Pipotiazine; Prochlorperazine; Promazine; Thioproperazine; Thioridazine; Trifluoperazine; Triflupromazine
- Antipsychotic adjunct - Pericyazine
- Sedative - Chlorpromazine; Methotrimeprazine; Thioridazine
DescriptionPhenothiazines (FEE-noe-THYE-a-zeens)
are
used to treat serious mental and emotional disorders, including schizophrenia
and other psychotic disorders. Some are used also to control agitation in
certain patients, severe nausea and vomiting, severe hiccups, and moderate
to severe pain in some hospitalized patients. Chlorpromazine is used also
in the treatment of certain types of porphyria, and with other medicines in
the treatment of tetanus. Phenothiazines may also be used for other conditions
as determined by your doctor.
Phenothiazines may cause unwanted, unattractive, and uncontrolled face
or body movements that may not go away when you stop taking the medicine.
They may also cause other serious unwanted effects. You and your doctor should
talk about the good this medicine will do as well as the risks of using it.
Also, your doctor should look for early signs of these effects at regular
visits. Your doctor may be able to stop or decrease some unwanted effects,
if they do occur, by changing your dose or by making other changes in your
treatment.
Phenothiazines are available only with your doctor's prescription in the
following dosage forms:
Oral
-
Chlorpromazine
-
Extended-release capsules (U.S.)
-
Oral concentrate (U.S. and Canada)
-
Syrup (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Fluphenazine
-
Elixir (U.S. and Canada)
-
Oral solution (U.S.)
-
Tablets (U.S. and Canada)
-
Mesoridazine
-
Oral solution (U.S.)
-
Tablets (U.S. and Canada)
-
Methotrimeprazine
-
Oral solution (Canada)
-
Tablets (Canada)
-
Pericyazine
-
Capsules (Canada)
-
Oral solution (Canada)
-
Perphenazine
-
Oral solution (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Prochlorperazine
-
Extended-release capsules (U.S.)
-
Oral solution (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Thioproperazine
-
Thioridazine
-
Oral solution (U.S. and Canada)
-
Oral suspension (U.S. and Canada)
-
Tablets (U.S. and Canada)
-
Trifluoperazine
-
Syrup (U.S. and Canada)
-
Tablets (U.S. and Canada)
Parenteral
-
Chlorpromazine
-
Injection (U.S. and Canada)
-
Fluphenazine
-
Injection (U.S. and Canada)
-
Mesoridazine
-
Methotrimeprazine
-
Perphenazine
-
Pipotiazine
-
Prochlorperazine
-
Injection (U.S. and Canada)
-
Promazine
-
Trifluoperazine
-
Triflupromazine
Rectal
-
Chlorpromazine
-
Suppositories (U.S. and Canada)
-
Prochlorperazine
-
Suppositories (U.S. and Canada)
Brand NamesSome commonly used brand names are:
In the U.S. -
- Chlorpromazine Hydrochloride Intensol 1
- Compazine 8
- Compazine Spansule 8
- Mellaril 11
- Mellaril Concentrate 11
- Mellaril-S 11
- Permitil 2
- Permitil Concentrate 2
- Prolixin 2
- Prolixin Concentrate 2
- Prolixin Decanoate 2
- Prolixin Enanthate 2
- Serentil 3
- Serentil Concentrate 3
- Stelazine 12
- Stelazine Concentrate 12
- Thorazine 1
- Thorazine Spansule 1
- Trilafon 6
- Trilafon Concentrate 6
- Vesprin 13
In Canada -
- Apo-Fluphenazine 2
- Apo-Perphenazine 6
- Apo-Thioridazine 11
- Apo-Trifluoperazine 12
- Chlorpromanyl-20 1
- Chlorpromanyl-40 1
- Largactil 1
- Largactil Liquid 1
- Largactil Oral Drops 1
- Majeptil 10
- Mellaril 11
- Modecate 2
- Modecate Concentrate 2
- Moditen Enanthate 2
- Moditen HCl 2
- Neuleptil 5
- Novo-Chlorpromazine 1
- Novo-Trifluzine 12
- Novo-Ridazine 11
- Nozinan 4
- Nozinan Liquid 4
- Nozinan Oral Drops 4
- Nu-Prochlor 8
- Piportil L 4 7
- PMS Fluphenazine 2
- PMS Perphenazine 6
- PMS Prochlorperazine 8
- PMS Thioridazine 11
- PMS Trifluoperazine 12
- Serentil 3
- Stelazine 12
- Stemetil 8
- Stemetil Liquid 8
Note:
|
For quick reference, the following phenothiazines are numbered
to match the corresponding brand names.
|
This information applies to the following medicines: |
1. |
Chlorpromazine (klor-PROE-ma-zeen)‡§ |
2. |
Fluphenazine (floo-FEN-a-zeen)‡§ |
3. |
Mesoridazine (mez-oh-RID-a-zeen) |
4. |
Methotrimeprazine (meth-oh-trye-MEP-ra-zeen)* |
5. |
Pericyazine (pair-ee-SYE-a-zeen)* |
6. |
Perphenazine (per-FEN-a-zeen)‡§ |
7. |
Pipotiazine (pip-oh-TYE-a-zeen)* |
8. |
Prochlorperazine (proe-klor-PAIR-a-zeen)‡§ |
9. |
Promazine (PROE-ma-zeen)*§ |
10. |
Thioproperazine (thye-oh-proe-PAIR-a-zeen)* |
11. |
Thioridazine (thye-oh-RID-a-zeen)‡ |
12. |
Trifluoperazine (trye-floo-oh-PAIR-a-zeen)‡§ |
13. |
Triflupromazine (trye-floo-PROE-ma-zeen)† |
Note:
|
This information does not
apply to Ethopropazine,Promethazine, Propiomazine, and Trimeprazine. |
* Not commercially available in the U.S. |
† Not commercially available in Canada |
‡ Generic name product may be available
in the U.S. |
§ Generic name product may be available
in Canada |
|