Rauwolfia Alkaloids and Thiazide Diuretics (Systemic)
Precautions While Using This Medicine
important that your doctor check your progress at regular visits to make sure
that this medicine is working properly.
Do not take other medicines unless they have been discussed
with your doctor
. This especially includes over-the-counter (nonprescription)
medicines for appetite control, asthma, colds, cough, hay fever, or sinus
problems, since they may tend to increase your blood pressure.
Before having any kind of surgery (including dental surgery), or emergency
treatment, tell the medical doctor or dentist in charge
that you are taking this medicine
This medicine may cause a loss of potassium from your body.
To help prevent this, your doctor may want you to:
eat or drink foods that have a high potassium content (for example,
orange or other citrus fruit juices), or
take a potassium supplement, or
take another medicine to help prevent the loss of the potassium in
the first place.
It is very important to follow these directions. Also, it is important
not to change your diet on your own. This is more important if you are already
on a special diet (as for diabetes), or if you are taking a potassium supplement
or a medicine to reduce potassium loss. Extra potassium may not be necessary
and, in some cases, too much potassium could be harmful.
Check with your doctor if you become sick and have severe or continuing
vomiting or diarrhea. These problems may cause you to lose additional water
This medicine may cause some people to become drowsy or less alert than
they are normally. This is more likely to happen when you begin to take it
or when you increase the amount of medicine you are taking. Make sure you know how you react to this medicine before you drive, use machines,
or do anything else that could be dangerous if you are not alert
Dizziness, lightheadedness, or fainting may occur,
especially when you get up from a lying or sitting position
. This is
more likely to occur in the morning. Getting up slowly may help. When you
get up from lying down, sit on the edge of the bed with your feet dangling
for 1 or 2 minutes. Then stand up slowly. If the problem continues or gets
worse, check with your doctor.
The dizziness, lightheadedness, or fainting is also more likely to occur
if you drink alcohol, stand for a long time, exercise, or if the weather is
hot. While you are taking this medicine, be careful to
limit the amount of alcohol you drink. Also, use extra care during exercise
or hot weather or if you must stand for a long time
In some patients, this medicine may cause mental depression. Tell your doctor right away
if you or anyone else notices unusual changes in your moods.
if you start having early-morning sleeplessness or unusually vivid
dreams or nightmares.
This medicine will add to the effects of alcohol and other CNS depressants
(medicines that slow down the nervous system, possibly causing drowsiness).
Some examples of CNS depressants are antihistamines or medicine for hay fever,
other allergies, or colds; sedatives, tranquilizers, or sleeping medicine;
prescription pain medicine or narcotics; barbiturates; medicine for seizures;
muscle relaxants; or anesthetics, including dental anesthetics. Check with your doctor before taking any of the above while you are taking
For diabetic patients
This medicine may raise blood sugar levels. While you are using this
medicine, be especially careful in testing for sugar in your urine. If you
have any questions about this, check with your doctor.
Some people who take this medicine may become more sensitive to sunlight
than they are normally. Exposure to sunlight, even for brief periods of time,
may cause severe sunburn; skin rash, redness, itching, or discoloration; or
vision changes. When you begin taking this medicine:
Stay out of direct sunlight, especially between the hours of 10:00
a.m. and 3:00 p.m., if possible.
Wear protective clothing, including a hat and sunglasses.
Apply a sun block product that has a skin protection factor (SPF)
of at least 15. Some patients may require a product with a higher SPF number,
especially if they have a fair complexion. If you have any questions about
this, check with your health care professional.
Do not use a sunlamp or tanning bed or booth.
If you have a severe reaction from the sun, check with your doctor.
This medicine often causes stuffiness in the nose. However, do not use
nasal decongestant medicines without first checking with your health care
This medicine may cause dryness of the mouth. For temporary relief, use
sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute.
However, if dry mouth continues for more than 2 weeks, check with your medical
doctor or dentist. Continuing dryness of the mouth may increase the chance
of dental disease, including tooth decay, gum disease, and fungus infections.