Newer blood-pressure drugs pose less diabetes risk
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More recent blood pressure treatments are less likely to be associated with diabetes than are older medicines, researchers said on Friday.
Their conclusions are based on a systematic review of 22 clinical trials involving 143,000 patients who did not have diabetes when they were started on the different high blood pressure medicines.
The propensity of some blood-pressure-lowering drugs to reduce glucose tolerance and trigger diabetes has been known for some time, but a meta-analysis of past clinical trials found the danger was less with angiotensin-receptor blockers and angiotensin-converting-enzyme inhibitors.
William Elliott of Rush University Medical Center, Chicago, and colleagues reported in the Lancet medical journal that the link between diabetes was lowest for angiotensin-receptor blockers and angiotensin-converting-enzyme inhibitors, followed by calcium-channel blockers, beta-blockers and diuretics.
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