3-rx.comCustomer Support
HomeAbout UsFAQContactHelp
News Center
Health Centers
Medical Encyclopedia
Drugs & Medications
Diseases & Conditions
Medical Symptoms
Med. Tests & Exams
Surgery & Procedures
Injuries & Wounds
Diet & Nutrition
Special Topics

\"$alt_text\"');"); } else { echo"\"$alt_text\""; } ?>

Join our Mailing List


You are here : 3-RX.com > Home > Fertility and pregnancy - Breast Cancer -

Breast cancer risk linked with fertility timing

Fertility and pregnancy • • Breast CancerFeb 14, 08

A longer interval between the age a woman first begins to menstruate and her age when she first gives birth is associated with an increased risk of breast cancer, the results of a study published in the American Journal of Epidemiology suggests.

Age at menstruation and first birth are “established risk factors for breast cancer,” Dr. Christopher I. Li, of the Fred Hutchinson Cancer Research Center, Seattle, and colleagues write. The interval between these ages may also influence breast cancer risk because the breast becomes more susceptible to carcinogenic exposure during this period period, they note. “However, few investigators have studied this relation.”

To investigate further, Li’s group used data from the Women’s Contraceptive and Reproductive Experiences Study (1994 to 1998), including 4,013 women with breast cancer and 4,069 women without breast cancer (the controls).

Among the white women, those who were premenopausal, had given birth and who also had an interval of at least 16 years from when they began to menstruate and their first birth had a 1.5-fold increased risk of breast cancer compared to those who had fewer than 5 years between these ages. This association was not observed among premenopausal African-American women.

The increased risks were mainly confined to women with hormone-receptor-positive tumors and tumors located in the breast lobules.

The results associating age at first full-term birth and breast cancer risk are generally consistent with previous results, but the findings regarding age at first menstruation are not, Li’s team adds.

“Epidemiologic studies of both premenopausal and postmenopausal women have consistently found that breast cancer risk is reduced 5 to 20 percent for each year (menstruation) is delayed,” they explain. However, in this study an older age at first (menstruation) was not associated with a reduced risk of breast cancer.”

SOURCE: American Journal of Epidemiology, January 2008.

Print Version
comments powered by Disqus

  Widespread agricultural contaminant impacts fish reproductive behavior
  Fat grafting technique improves results of breast augmentation
  UW research shows sensor technology may help improve accuracy of clinical breast exams
  Supreme Court declines to hear new contraception cases
  Generic Breast Cancer Drugs Boost Adherence
  New models of drug-resistant breast cancer point to better treatments
  Breast tomosynthesis increases cancer detection and reduces recall rates
  2 views are better than 1 in 3-D breast screening
  Arkansas governor vetoes bill banning abortions at 20 weeks
  Study reveals genomic similarities between breast cancer and ovarian cancers
  Moderate exercise tied to lower breast cancer risk
  In Vitro Fertilization Less Successful With Alternative Fertility Treatments


Home | About Us | FAQ | Contact | Advertising Policy | Privacy Policy | Bookmark Site